Placental tissue grafts
View Patent ↗A method for preparing placenta membrane tissue grafts for medical use, includes obtaining a placenta from a subject, cleaning the placenta, separating the chorion tissue from the amniotic membrane, mounting a selected layer of either the chorion tissue or the amniotic membrane onto a drying fixture, dehydrating the selected layer on the drying fixture, and cutting the selected layer into a plurality of tissue grafts. Preferably, the drying fixture includes grooves or raised edges that define the outer contours of each desired tissue graft, after they are cut, and further includes raised or indented logos that emboss the middle area of the tissue grafts during dehydration and that enables an end user to distinguish the top from the bottom side of the graft. The grafts are comprised of single layers of amnion or chorion, multiple layers of amnion or chorion, or multiple layers of a combination of amnion and chorion.
1. A dehydrated, laminated tissue graft, wherein the tissue graft is produced by a process consisting of:
isolating an intact amnion layer;
isolating a chorion layer;
washing and substantially cleaning the amnion layer and the chorion layer;
laminating the amnion layer and the chorion layer together; and
dehydrating the laminated graft to produce the dehydrated, laminated tissue graft.
2. The tissue graft of claim 1 , wherein the washing is carried out in an antibiotic solution.