Novel Succinate Salt of O-Desmethyl-Venlafaxine
A novel salt of O-desmethyl venlafaxine is provided, O-desmethylvenlafaxine succinate. Pharmaceutical compositions, dosage forms and methods of use are also provided.
1 . An oral dosage form comprising O-desmethyl venlafaxine succinate, wherein the oral dosage form is a tablet.
2 . An oral dosage form comprising O-desmethyl venlafaxine succinate, wherein the oral dosage form is a capsule.
3 . The oral dosage form of claim 1 or 2 , wherein the oral dosage form comprises from about 30% to about 50% by weight of O-desmethyl venlafaxine succinate.
4 . The oral dosage form of claim 1 or 2 , wherein the oral dosage form comprises from about 32% to about 44% by weight of O-desmethyl venlafaxine succinate.
5 . The oral dosage form of claim 1 or 2 , wherein the oral dosage form comprises about 50% by weight of O-desmethyl venlafaxine succinate.
6 . The oral dosage form of claim 1 or 2 , wherein the oral dosage form comprises about 44% by weight of O-desmethyl venlafaxine succinate.
7 . The dosage form of claim 1 or 2 , wherein each dosage form contains from about 15 mg to about 350 mg of O-desmethyl venlafaxine succinate.
8 . The dosage form of claim 1 or 2 , wherein each dosage form contains from about 10 mg to about 1000 mg of O-desmethyl venlafaxine succinate.
9 . The dosage form of claim 1 or 2 , wherein each dosage form contains 200 mg of O-desmethyl venlafaxine succinate.