IP Library Granted Patent US 7,921,657
Granted Patent B2
US 7,921,657 · App. 11/846,226 · Granted Apr 12, 2011

Methods and systems for cryogenic cooling

Assignee: Endocare, Inc.
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Quick Facts
Patent No.
US 7,921,657
App. No.
11/846,226
Granted
Apr 12, 2011
Kind
B2
Abstract

Methods and systems are provided for cooling an object with a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature. A pressure of the cryogen is raised above a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock. Thereafter, the cryogen is placed in thermal communication with the object to increase a temperature of the cryogen along a thermodynamic path that maintains the pressure greater than the critical-point pressure for a duration that the cryogen and object are in thermal communication.

Claims (19)

1. A method for cooling the surface of a cryoprobe using a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature, the method comprising:

raising a pressure of cryogen above its critical-point pressure, said cryogen comprising N 2 ; and

thereafter, placing the cryogen in thermal communication with the surface of a cryoprobe to increase a temperature of the cryogen along a thermodynamic path that maintains the pressure greater than the critical-point pressure for the duration that the cryogen and said surface are in thermal communication.

2. The method recited in claim 1 wherein the thermodynamic path increases the temperature of the cryogen to an ambient temperature.

3. The method recited in claim 2 further comprising reducing the pressure of the cryogen to an ambient pressure after removing the cryogen from thermal communication with said surface.

4. The method recited in claim 1 further comprising, after raising the pressure of the cryogen above its critical-point pressure and prior to placing the cryogen in thermal communication with said surface, reducing the temperature of the cryogen without decreasing the pressure of the cryogen below its critical-point pressure.

5. The method recited in claim 4 wherein reducing the temperature of the cryogen comprises placing the cryogen in thermal communication with a second liquid cryogen having a temperature lower than the temperature of the cryogen.

6. The method recited in claim 5 wherein the cryogen and second cryogen are chemically identical.

7. The method recited in claim 5 wherein the second liquid cryogen is substantially at ambient pressure.

8. The method recited in claim 1 wherein raising the pressure of the cryogen above its critical-point pressure comprises:

placing the cryogen within a thermally insulated tank; and

applying heat within the thermally insulated tank at least until a predetermined pressure within the thermally insulated tank is reached.

9. A system for cooling the surface of a cryoprobe using a cryogen having a critical point defined by a critical-point pressure and a critical-point temperature, the system comprising:

means for raising a pressure of cryogen above a pressure value determined to provide the cryogen at a reduced molar volume that prevents vapor lock, said cryogen comprising N 2 ; and

means for thereafter placing the cryogen in thermal communication with the surface of a cryoprobe to increase a temperature of the cryogen along a thermodynamic path that maintains a pressure greater than determined pressure value for the duration that the cryogen and said surface are in thermal communication.

10. The system recited in claim 9 further comprising means for reducing the pressure of the cryogen to an ambient pressure after removing the cryogen from thermal communication with said surface.

11. The system recited in claim 9 further comprising means for reducing the temperature of the cryogen without decreasing the pressure of the cryogen below its critical-point pressure after raising the pressure of the cryogen above its critical-point temperature and prior to placing the cryogen in thermal contact with said surface.

12. The system recited in claim 11 wherein the means for reducing the temperature of the cryogen comprises means for placing the cryogen in thermal communication with a second liquid cryogen having a temperature lower than the temperature of the cryogen.

13. The system recited in claim 9 wherein the means for raising the pressure of the cryogen comprises means for applying heat to the cryogen within a thermally insulated holding means until a predetermined pressure within the thermally insulated holding means is reached.

Assignments (5)
SECURITY INTEREST Recorded Jul 31, 2024
From: ADAGIO MEDICAL HOLDINGS, INC.
To: ALLEGRO MANAGEMENT LLC
Reel/Frame 068236/0236 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2014
From: CRYODYNAMICS, LLC
To: ADAGIO MEDICAL, INC.
Reel/Frame 032187/0117 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2007
From: LITTRUP, PETER J.; BABKIN, ALEXEI V.; DUNCAN, ROBERT; BOLDAREV, SERGEY
To: MEDIPHYSICS LLP
Reel/Frame 019761/0762 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 29, 2007
From: MEDIPHYSICS LLP
To: CRYODYNAMICS, LLC
Reel/Frame 019762/0584 →
LICENSE Recorded Aug 29, 2007
From: CRYODYNAMICS, LLC
To: ENDOCARE, INC.
Reel/Frame 019762/0866 →
Continuity (6)
Division 10952531 · Sep 27, 2004
Continuation In Part 10757768 · Jan 14, 2004
Continuation In Part 10757769 · Jan 14, 2004
Provisional Application 60440541 · Jan 15, 2003
Provisional Application 60440662 · Jan 15, 2003
Related Publication 20080173028A1 · Jul 24, 2008