Xanthine phosphodiesterase V inhibitors
View Patent ↗A xanthine phosphodiesterase V inhibitor having the formula (I), with the variables defined herein, which is especially useful for treating male (erectile) and female sexual dysfunction and other physiological disorders: For example, a representative compound of the invention is:
1. A pharmaceutical composition comprising an effective amount of a compound of the formula:
or a pharmaceutically acceptable salt thereof and an endothelin receptor agonist.
2. A method for treating pulmonary hypertension in a patient in need thereof which comprises administering to said patient an effective amount of the pharmaceutical composition according to claim 1 .
3. A method for treating pulmonary hypertension in a patient in need thereof which comprises administering to said patient an effective amount of a compound of the formula
or a pharmaceutically acceptable salt thereof to said patient.