Energy status of an individual by enhanced usage of an endogenous fuel source
View Patent ↗The present invention relates to a method of improving the energy status of an individual by enhancing the usage of lactate. Improved lactate usage is accomplished through a composition comprising lactate precursors, adrenergic receptor agonists and insulinotropic agents.
1. A composition for improving the usage of lactate for energy in a mammal comprising; one or more adrenergic receptor agonists; one or more lactate precursors; and one or more insulinotropic agents.
2. The composition of claim 1 wherein; the adrenergic receptor agonist is caffeine in an amount from about 5 mg to about 500 mg.
3. The composition of claim 2 wherein; the lactate precursor is selected from the group consisting of: glutamine, and pyruvate; and wherein the insulinotropic agent is selected from the group consisting of: leucine, arginine, methyl pyruvate, and methyl succinate.
4. The composition of claim 2 wherein; the lactate precursor is glutamine; and the insulinotropic agent is leucine.
5. The composition of claim 4 wherein; the amount of glutamine is from about 0.05 g to about 5.00 g; and the amount of leucine or derivative of leucine is from about 10 mg to about 7.50 g.
6. The composition of claim 2 wherein; the lactate precursor is glutamine; and the insulinotropic agent is arginine.
7. The composition of claim 6 wherein; the amount of glutamine is from about 0.05 g to about 5.00 g; and the amount of arginine is from about 50 mg to about 5.00 g.
8. The composition of claim 2 wherein; the lactate precursor is pyruvate; and the insulinotropic agent is leucine.
9. The composition of claim 8 wherein; the amount of pyruvate is from about 1 mg to about 1000 mg; and the amount of leucine is from about 10 mg to about 7.50 g.
10. The composition of claim 2 wherein; the lactate precursor is pyruvate; and the insulinotropic agent is arginine.
11. The composition of claim 10 wherein; the amount of pyruvate is from about 1 mg to about 1000 mg; and the amount of arginine is from about 50 mg to about 5.00 g.
12. A method of improving the usage of lactate for energy in a mammal comprising the step of administering to the mammal a composition comprising; one or more adrenergic receptor agonist; one or more lactate precursors; and one or more insulinotropic agents.
13. The method of claim 12 wherein; the adrenergic receptor agonist is caffeine in an amount from about 5 mg to about 500 mg.
14. The method of claim 13 wherein; the lactate precursor is selected from the group consisting of: glutamine, and pyruvate; and the insulinotropic agent is selected from the group consisting of: leucine, arginine, methyl pyruvate, and methyl succinate.
15. The method of claim 12 wherein; the lactate precursor is glutamine; and the insulinotropic agent is leucine.
16. The method of claim 15 wherein; the amount of glutamine is from about 0.05 g to about 5.00 g; and the amount of leucine is from about 10 mg to about 7.50 g.
17. The method of claim 12 wherein; the lactate precursor is glutamine; and the insulinotropic agent is arginine.
18. The method of claim 17 wherein; the amount of glutamine is from about 0.05 g to about 5.00 g; and the amount of arginine is from about 50 mg to about 5.00 g.
19. The method of claim 12 wherein; the lactate precursor is pyruvate; and the insulinotropic agent is leucine.
20. The method of claim 19 wherein; the amount of pyruvate is from about 1 mg to about 1000 mg; and the amount of leucine is from about 10 mg to about 7.50 g.
21. The method of claim 12 wherein; the lactate precursor is pyruvate; and the insulinotropic agent is arginine.
22. The method of claim 21 wherein; the amount of pyruvate is from about 1 mg to about 1000 mg; and the amount of arginine is from about 50 mg to about 5.00 g.