Method for preventing or treating the development of respiratory allergies
View Patent ↗The present invention is directed to a novel method for preventing or treating the development of respiratory allergies. The method comprises prenatal and/or postnatal administration of a therapeutically effective amount of LGG.
1. A method for preventing or reducing the production of serum IgE antibodies in an infant, the method comprising prenatally administering to the infant an effective amount of Lactobacillus rhamnosus GG prior to allergic sensitization of the infant.
2. The method of claim 1 , wherein the prenatal administration of Lactobacillus GG comprises ingestion of Lactobacillus GG by the pregnant mother of the unborn infant.
3. The method of claim 1 , wherein the amount of Lactobacillus GG administered to the infant is between about 1×10 4 and 1×10 12 cfu/L/kg/day.
4. The method of claim 1 , wherein the amount of Lactobacillus GG administered to the infant is between about 1×10 6 and 1×10 9 cfu/L/kg/day.
5. A method for preventing or reducing the production of serum IgE antibodies in an infant, the method comprising postnatally administering to the infant an effective amount of Lactobacillus rhamnosus GG prior to allergic sensitization of the infant.
6. The method of claim 5 , wherein the postnatal administration of Lactobacillus GG comprises ingestion of Lactobacillus GG by the infant's mother followed by breast feeding of the infant by the mother.
7. The method of claim 5 , wherein the postnatal administration of Lactobacillus GG comprises incorporation of the Lactobacillus GG into an infant formula and consumption of the formula by the infant.
8. The method of claim 5 , wherein the amount of Lactobacillus GG administered to the infant is between about 1×10 4 and 1×10 12 cfu/L/kg/day.
9. The method of claim 5 , wherein the amount of Lactobacillus GG administered to the infant is between about 1×10 6 and 1×10 9 cfu/L/kg/day.
10. The method of claim 5 , wherein the method further comprises administering to the infant at least one additional probiotic.
11. The method of claim 5 , wherein the method further comprises administering to the infant at least one prebiotic.