System and method for endoscopic treatment of tissue

1. A ligating barrel for use with an endoscope, the ligating barrel comprising:

a rigid first tubular section having a lumen extending there through, the lumen having a fixed internal diameter, at least two inwardly projecting tabs providing a decreased diameter along a portion of the lumen, the lumen being adapted to contain a distal end of an endoscope, the inwardly projecting tabs being configured to directly engage the distal end of the endoscope when contained within the lumen, and

a tapered elastomeric second tubular section having an expandable diameter that is expandable from a minimum diameter that is less than the fixed internal diameter of the lumen of the first section, the second section comprising internal ribbing for providing a friction fit and direct contact with the distal end of an endoscope, the internal ribbing comprising a plurality of circumferentially oriented ribs having a semi-circular cross-section and encircling an interior surface of the second section.

2. The ligating barrel of claim 1 wherein said plurality of circumferentially oriented ribs are disposed along the interior surface of the second section at spaced apart locations, the spacing between adjacent ribs being larger than a width of each of the ribs.

3. A ligating barrel adapted to be removably attached to an endoscope, the ligating barrel comprising a tubular band deployment section and a tubular conformable section, said band deployment section having an internal first diameter, said conformable section comprising an internal second diameter and a means for adjusting the internal second diameter of the conformable section for direct attachment to a distal end of an endoscope,

wherein the distal end of the endoscope comprises an external diameter that is substantially smaller than the first diameter of the band deployment section, and

wherein the conformable section further comprises a plurality of spaced apart surface features having a curvilinear engagement surface that is configured to frictionally and directly engage the distal end of the endoscope, the surface features each having a width that is less than the spacing therebetween.

4. The ligating barrel of claim 3 wherein said means comprises one of a collet, a flexible helical band, and a plurality of screws.

5. The ligating barrel of claim 3 wherein said means comprises a tapered elastomeric second section having an expandable diameter with internal ribbing for providing a friction fit with the distal end of an endoscope.

6. The ligating barrel of claim 3 further comprising:

an endoscope having a distal end wherein the ligating barrel is disposed on the distal end of the endoscope.

7. The ligating barrel of claim 6 further comprising an activating component disposed on a proximal portion of the endoscope, the activating component being operably connected to one or more ligating bands disposed about the band deployment section of the ligating barrel.

8. The ligating barrel of claim 7 further comprising an activation line operably connected between the activating component and the ligating barrel.

9. The ligating barrel of claim 7 wherein an activation line is operably connected between the activating component and the one or more bands, the activating line extending through a working channel of the endoscope.