IP Library › Patent Application 11888511
Patent Application
App. No. 11/888,511

Compositions and methods for coating medical implants

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Quick Facts
Patent No.
US None
App. No.
11/888,511
Abstract

Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.

Claims (6)

1 . A composition, comprising a polymer and a fluoropyrimidine wherein said fluoropyrimidine is present in said composition at a concentration of less than 10 −4 M.

2 . The composition according to claim 1 wherein said fluoropyrimidine is present in said composition at a concentration of less than any one of 10 −5 M, 10 −6 M, or 10 −7 M.

3 . The composition according to claim 1 wherein said polymer is a non-biodegradable polymer.

4 . The composition according to claim 1 wherein said polymer is a polyurethane.

5 . The composition according to claim 1 wherein said polymer is a poly(lactide-co-glycolide).

6 . The composition according to claim 1 wherein said fluoropyrimidine is 5-fluorouracil.