Dynamically variable filter
View Patent ↗A method of processing a signal pertaining to at least one electrical property of an organ of a subject is disclosed. The method comprises determining a physiological condition of the subject, selecting a frequency band, filtering the signal according to the frequency band, and dynamically adapting the frequency band in response to a change in the physiological condition.
1. Apparatus for monitoring at least one electrical property of an organ of a subject, comprising:
an input unit for receiving input radiofrequency signals sensed from the organ;
a signal processing unit for processing said input radiofrequency signals to provide processed input signals, said processing unit comprising a phase shift determinator configured for determining a phase shift of said input signal relative to an output radiofrequency signal transmitted to the organ;
a filtering unit configured for filtering said processed signals using dynamically variable band pass filter having a lower frequency bound and an upper frequency bound, wherein at least one of said frequency bounds is adapted in response to a change in a physiological condition of the subject, to thereby provide filtered signals, wherein said physiological condition is a heart rate of the subject and wherein at least one of said lower frequency bound and said upper frequency bound is a linear function of said heart rate; and
a data processor for calculating at least one quantity based on said phase shift, wherein said at least one quantity is selected from the group consisting of a stroke volume, a cardiac output, a brain intra luminal blood volume and blood flow.
2. The apparatus of claim 1 , wherein said lower bound is about 0.9*(HR/60) Hz at all times, wherein said HR is said heart rate in units of beats per minute.
3. The apparatus of claim 1 , wherein said upper frequency bound is about 6+1.5*[(HR/60)−1] Hz at all times, wherein said HR is said heart rate in units of beats per minute.
4. The apparatus of claim 1 , wherein said input radiofrequency signals are indicative of impedance of the organ.
5. The apparatus of claim 1 , wherein said input radiofrequency signals are indicative of hemodynamic reactance of the organ.
6. The apparatus of claim 1 , wherein said signal processing unit comprises an analog filter for filtering said input radiofrequency signals.
7. The apparatus of claim 1 , wherein said signal processing unit comprises an envelope elimination unit designed and configured to reduce or eliminate amplitude modulation of said filtered signals, so as to provide signals of substantially constant envelope.
8. The apparatus of claim 7 , wherein said envelope elimination unit is designed and configured to maintain a phase modulation of said signals.
9. The apparatus of claim 1 , wherein said signal processing unit comprises a mixer designed and configured to mix said input radiofrequency signals and said output radiofrequency signals transmitted to the organ so as to provide a mixed radiofrequency signal.
10. The apparatus of claim 9 , wherein said mixer is operable to provide a radiofrequency sum and a radiofrequency difference.
11. A system for monitoring at least one electrical property of an organ of a subject, comprising:
a radiofrequency generator for generating output radiofrequency signals;
a plurality of electrodes, designed to be connectable to the skin of the subject, said electrodes being for transmitting said output radiofrequency signals to the organ and for sensing input radiofrequency signals from the organ; and
the apparatus of claim 1 .