Cross-linked glycopeptide-cephalosporin antibiotics
View Patent ↗This invention provides cross-linked glycopeptides—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
1. A compound of the formula:
2. A pharmaceutically acceptable salt of a compound of the formula:
3. A hydrochloride salt of a compound of the formula:
4. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a compound of the formula:
5. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a pharmaceutically acceptable salt of a compound of the formula:
6. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of a hydrochloride salt of a compound of the formula: