Methods and systems relating to mitochondrial DNA phenotypes
In one aspect, a system includes, but is not limited to, at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to, one or more instructions for determining at least one correlation between at least one mitochondrial DNA-influencing event and at least one aspect of mitochondrial DNA phenotype information regarding at least one individual.
1 . A method comprising:
determining a similarity or a dissimilarity between at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual and at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual, wherein the at least one second individual had been influenced by at least one mitochondrial DNA-influencing event.
2 . (canceled)
3 . The method of claim 1 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mitochondrial DNA sequence.
4 . The method of claim 1 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding heteroplasmy.
5 . The method of claim 1 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding one or more maternal relatives of the at least one first individual.
6 . The method of claim 1 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mosaicism of the at least one first individual.
7 .- 9 . (canceled)
10 . The method of claim 1 , wherein the at least one mitochondrial DNA-influencing event includes at least one medical therapy.
11 . The method of claim 1 , wherein the at least one mitochondrial DNA-influencing event includes at least one environmental event.
12 . The method of claim 1 , further comprising:
one or more instructions for correlating the at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual with previous mitochondrial DNA information regarding the at least one second individual, wherein the previous mitochondrial DNA information was ascertained prior to the mitochondrial DNA-influencing event.
13 . (canceled)
14 . The method of claim 1 , further comprising:
one or more instructions for suggesting at least one intervention strategy for the at least one first individual in reference to the at least one correlation.
15 . A system comprising:
at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to:
one or more instructions for determining at least one correlation between at least one mitochondrial DNA-influencing event and at least one aspect of mitochondrial DNA phenotype information regarding at least one individual.
16 . (canceled)
17 . The system of claim 15 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one individual includes information regarding mitochondrial DNA sequence.
18 . The system of claim 15 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one individual includes information regarding heteroplasmy.
19 . The system of claim 15 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding an individual includes information regarding one or more maternal relatives of the at least one individual.
20 . The system of claim 15 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one individual includes information regarding mosaicism of at least one individual.
21 .- 23 . (canceled)
24 . The system of claim 15 , wherein the at least one mitochondrial DNA-influencing event includes at least one medical therapy.
25 . The system of claim 15 , wherein the at least one mitochondrial DNA-influencing event includes at least one environmental event.
26 . The system of claim 15 , further comprising:
one or more instructions for correlating the at least one aspect of mitochondrial DNA phenotype information regarding at least one individual with previous mitochondrial DNA information regarding the at least one individual, wherein the previous mitochondrial DNA information was ascertained prior to the mitochondrial DNA-influencing event.
27 . (canceled)
28 . The system of claim 15 , further comprising:
one or more instructions for suggesting at least one intervention strategy in reference to the at least one correlation.
29 . A system comprising:
at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to:
one or more instructions for determining a similarity or a dissimilarity between at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual and at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual, wherein the at least one second individual had been influenced by at least one mitochondrial DNA-influencing event.
30 . (canceled)
31 . The system of claim 29 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mitochondrial DNA sequence.
32 . The system of claim 29 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding heteroplasmy.
33 . The system of claim 29 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding one or more maternal relatives of the at least one first individual.
34 . The system of claim 29 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mosaicism of the at least one first individual.
35 .- 37 . (canceled)
38 . The system of claim 29 , wherein the at least one mitochondrial DNA-influencing event includes at least one medical therapy.
39 . The system of claim 29 , wherein the at least one mitochondrial DNA-influencing event includes at least one environmental event.
40 . The system of claim 29 , further comprising:
one or more instructions for correlating the at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual with previous mitochondrial DNA information regarding the at least one second individual, wherein the previous mitochondrial DNA information was ascertained prior to the mitochondrial DNA-influencing event.
41 . (canceled)
42 . The system of claim 29 , further comprising:
one or more instructions for suggesting at least one intervention strategy for the at least one first individual in reference to the at least one correlation.
43 . A system comprising:
at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to:
one or more instructions for determining one or more correlations between at least one aspect of mitochondrial DNA phenotype information obtained regarding at least one first individual and information regarding at least one mitochondrial DNA-influencing event in relation to the at least one first individual; and
one or more instructions for applying at least one of the one or more correlations to at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual.
44 . The system of claim 43 , wherein the at least one mitochondrial DNA-influencing event includes at least one medical therapy.
45 . The system of claim 43 , wherein the at least one mitochondrial DNA-influencing event includes at least one environmental event.
46 . The system of claim 43 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mitochondrial DNA sequence.
47 . (canceled)
48 . The system of claim 43 , further comprising:
one or more instructions for predicting at least one mitochondrial DNA-influencing event influencing the at least one second individual.
49 . The system of claim 43 , further comprising:
one or more instructions for suggesting at least one intervention strategy for one or more of the at least one second individual.
50 . A system comprising:
at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to:
one or more instructions for determining one or more correlations between at least one aspect of mitochondrial DNA phenotype information obtained regarding at least one first individual and information regarding at least one medical therapy in relation to the at least one first individual; and
one or more instructions for applying at least one of the one or more correlations to at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual.
51 . The system of claim 50 , wherein the at least one medical therapy includes at least one therapeutic agent.
52 . The system of claim 50 , wherein the at least one medical therapy includes at least one energy-based procedure.
53 . The system of claim 50 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mitochondrial DNA sequence.
54 . (canceled)
55 . The system of claim 50 , further comprising:
one or more instructions for suggesting at least one intervention strategy for one or more of the at least one second individual.
56 . A system comprising:
at least one computer program for use with at least one computer system and wherein the computer program includes a plurality of instructions, including but not limited to:
one or more instructions for determining one or more correlations between at least one aspect of mitochondrial DNA phenotype information obtained regarding at least one first individual and information regarding at least one environmental event in relation to the at least one first individual; and
one or more instructions for applying at least one of the one or more correlations to at least one aspect of mitochondrial DNA phenotype information regarding at least one second individual.
57 . The system of claim 56 , wherein the at least one environmental event includes at least one environmental pollutant.
58 . The system of claim 56 , wherein the at least one environmental event includes at least one toxin.
59 . The system of claim 56 , wherein the at least one aspect of mitochondrial DNA phenotype information regarding at least one first individual includes information regarding mitochondrial DNA sequence.
60 . (canceled)
61 . The system of claim 56 , further comprising:
one or more instructions for predicting at least one environmental event influencing the at least one second individual.
62 . The system of claim 56 , further comprising:
one or more instructions for suggesting at least one intervention strategy for one or more of the at least one second individual.