IP Library › Granted Patent US 8,008,022
Granted Patent B2
US 8,008,022 · App. 11/908,691 · Granted Aug 30, 2011

Methods and kit for detecting breast cancer

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Quick Facts
Patent No.
US 8,008,022
App. No.
11/908,691
Granted
Aug 30, 2011
Kind
B2
Abstract

The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary proteins thereof, as compared to normal control or benign tissue is indicative of breast cancer.

Claims (8)

1. A kit for diagnosing breast cancer comprising:

a) an antibody-based binding moiety that specifically binds to UbcH1,

b) an antibody-based binding moiety that specifically binds to UbcH2,

c) an antibody-based binding moiety that specifically binds to UbcH5, and

d) an antibody-based binding moiety that specifically binds to eEF1A.

2. A kit for diagnosing ductal breast carcinoma comprising:

a) an antibody-based binding moiety that specifically binds to UbcH5, and

b) an antibody-based binding moiety that specifically binds to eEF1A.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 2, 2013
From: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
To: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
Reel/Frame 031700/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 28, 2008
From: MADURA, KIRAN; CHEN, LI
To: UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
Reel/Frame 021299/0493 →