IP Library › Granted Patent US 7,998,499
Granted Patent B2
US 7,998,499 · App. 11/923,880 · Granted Aug 16, 2011

Calcium-containing bone implants

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Quick Facts
Patent No.
US 7,998,499
App. No.
11/923,880
Granted
Aug 16, 2011
Kind
B2
Abstract

This invention relates to a method for preparing a porous bone implant containing a calcium-based mineral. The method includes immersing a porous matrix in an acidic solution containing a calcium-based mineral; removing the matrix from the solution; and exposing the matrix to an alkali to neutralize the acidic solution, thereby causing precipitation of the calcium-based mineral to obtain a porous bone implant containing a calcium-based mineral.

Claims (6)

1. A porous bone implant comprising a porous polymer-based matrix and a calcium-based mineral disposed on the surface of the matrix and inside the body of the matrix, wherein the amount of the calcium-based mineral per unit area on the surface of the matrix is greater than the amount of the calcium-based mineral per unit area inside the body of the matrix.

2. The bone implant of claim 1 , wherein the matrix is a collagen-based matrix.

3. The bone implant of claim 1 , wherein the matrix is a polysaccharide-based matrix.

4. The bone implant of claim 1 , wherein the calcium-based mineral is apatite, calcium phosphate, calcium carbonate, or a mixture thereof.

5. The bone implant of claim 4 , wherein the matrix is a collagen-based matrix.

6. The bone implant of claim 4 , wherein the matrix is a polysaccharide-based matrix.

Assignments (9)
RELEASE OF SECURITY INTEREST Recorded Jan 26, 2026
From: GOLUB CAPITAL MARKETS LLC, AS ADMINISTRATIVE AGENT
To: COLLAGEN MATRIX, INC.
Reel/Frame 073583/0580 →
SECURITY INTEREST Recorded Jan 26, 2026
From: COLLAGEN MATRIX, INC.
To: GOLUB CAPITAL MARKETS LLC, AS COLLATERAL AGENT
Reel/Frame 073583/0614 →
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT R/F 049933/0378 Recorded Aug 1, 2024
From: THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY
To: COLLAGEN MATRIX, INC.
Reel/Frame 068256/0450 →
FIRST LIEN PATENT SECURITY AGREEMENT Recorded Aug 1, 2019
From: COLLAGEN MATRIX, INC.
To: GOLUB CAPITAL, LLC
Reel/Frame 051594/0368 →
SECURITY INTEREST Recorded Aug 1, 2019
From: COLLAGEN MATRIX, INC.
To: THE NORTHWESTERN MUTUAL LIFE INSURANCE COMPANY
Reel/Frame 049933/0378 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Aug 1, 2019
From: CAPITAL ONE, NATIONAL ASSOCIATION
To: COLLAGEN MATRIX, INC.
Reel/Frame 049934/0317 →
ASSIGNMENT OF INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Nov 14, 2015
From: GENERAL ELECTRIC CAPITAL CORPORATION, AS RETIRING AGENT
To: HEALTHCARE FINANCIAL SOLUTIONS, LLC, AS SUCCESSOR AGENT
Reel/Frame 037111/0808 →
SECURITY INTEREST Recorded Oct 23, 2014
From: COLLAGEN MATRIX, INC.
To: GENERAL ELECTRIC CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 034021/0474 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 26, 2007
From: LI, SHU-TUNG; YUEN, DEBBIE; CHEN, HUI-CHEN
To: COLLAGEN MATRIX, INC.
Reel/Frame 020019/0294 →