IP Library › Granted Patent US 7,707,970
Granted Patent B2
US 7,707,970 · App. 11/937,642 · Granted May 4, 2010

Vaccine against salmonid rickettsial septicaemia based on

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Quick Facts
Patent No.
US 7,707,970
App. No.
11/937,642
Granted
May 4, 2010
Kind
B2
Abstract

A vaccine based on live Arthrobacter cells is useful in preventing piscirickettsiosis in fish.

Claims (21)

1. A method of treating or preventing a disease in a fish, the method comprising:

administering to the fish an immunogenic composition comprising an Arthrobacter , wherein the disease is caused by Piscirickettsia salmonis.

2. The method of claim 1 , wherein the disease is piscirickettsiosis.

3. The method of claim 1 , wherein the fish is a salmonid fish.

4. The method of claim 1 , wherein the fish is Salmo salar.

5. The method of claim 1 , wherein the fish is an Ocnorhyncus species.

6. The method of claim 1 , wherein the fish is selected from the group consisting of: Oncorhyncus kisutch, Oncorhyncus tshawytscha, Oncorhyncus masou, Oncorhyncus gorbuscha , and Oncorhyncus mykiss.

7. The method of claim 1 , wherein the fish is an Oncorhyncus kisutch.

8. The method of claim 1 , wherein the Arthrobacter is live.

9. The method of claim 8 , wherein the composition further comprises a killed Arthrobacter.

10. The method of claim 1 , wherein the Arthrobacter is killed.

11. The method of claim 1 , wherein the Arthrobacter is an Arthrobacter species deposited under ATCC accession no. 55921.

12. The method of claim 1 , wherein the Arthrobacter is a species having a 16S rDNA sequence that is identical to or less than 3% divergent to the 16S rDNA sequence of an Arthrobacter species deposited under ATCC accession no. 55921.

13. The method of claim 1 , wherein the composition further comprises at least one immunogen other than the Arthrobacter.

14. The method of claim 13 , wherein the at least one immunogen is a Piscirickettsia salmonis antigen.

15. The method of claim 14 , wherein the Piscirickettsia salmonis antigen is a nucleic acid expression vector capable of expressing the Piscirickettsia salmonis antigen.

16. The method of claim 13 , wherein the at least one immunogen is a Piscirickettsia salmonis.

17. The method of claim 16 , wherein the Piscirickettsia salmonis is inactivated.

18. The method of claim 16 , wherein the Piscirickettsia salmonis is killed.

19. The method of claim 1 , wherein the administering is by intraperitoneal injection of the fish.

20. The method of claim 1 , wherein the administering is by immersion of the fish.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2024
From: NOVARTIS AG
To: ELANCO TIERGESUNDHEIT AG (F/K/A NOVARTIS TIERGESUNDHEIT AG),
Reel/Frame 067136/0484 →
CHANGE OF NAME Recorded Aug 25, 2017
From: NOVARTIS TIERGESUNDHEIT AG
To: ELANCO TIERGESUNDHEIT AG
Reel/Frame 043402/0486 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2015
From: NOVARTIS AG
To: NOVARTIS TIERGESUNDHEIT AG
Reel/Frame 034926/0390 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2010
From: SALONIUS, KIRA
To: NOVARTIS ANIMAL HEALTH US, INC.
Reel/Frame 023967/0133 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2010
From: GRIFFITHS, STEVEN GARETH
To: NOVARTIS ANIMAL HEALTH US, INC.
Reel/Frame 023967/0290 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 22, 2010
From: NOVARTIS ANIMAL HEALTH US, INC.
To: NOVARTIS AG
Reel/Frame 023967/0316 →