Graft for hysterotomy closure
View Patent ↗A graft and method of using a graft are described that should decrease the incidence of abnormal placentation and uterine rupture that result from cesarean section and restore the anatomic integrity of the uterus at a hysterotomy surgical site, while not disturbing the involution of the postpartum uterus.
1. The use of a biological tissue graft that has been rendered non-cellular, in the manufacture of a medicament for treating a hysterotomy incision by interposing the biological tissue graft between two tissue faces created by the hysterotomy incision.
2. The use of claim 1 , wherein the biological tissue graft comprises submucosa.
3. A method for repairing a hysterotomy site comprising:
providing a graft, wherein the graft comprises at least one collagenous material capable of remodeling;
interposing the graft between a first incised tissue face and a second incised tissue face of the the hysterotomy site;
attaching the graft to the first and second incised tissue faces of the hysterotomy site; and
closing the hysterotomy site.
4. The method of claim 3 , wherein the closing the hysterotomy site further comprises using a suture, staple, or glue.
5. The method of claim 3 , wherein the graft is seeded with cells, biomolecules, or bioactives.
6. The method of claim 3 , wherein the graft further comprises a coating.
7. The method of claim 3 , wherein the collagenous material comprises a suspension, gel or a foam tube.