IP Library Granted Patent US 8,491,525
Granted Patent B2
US 8,491,525 · App. 11/942,080 · Granted Jul 23, 2013

Systems, apparatus and associated methods for needleless delivery of therapeutic fluids

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Quick Facts
Patent No.
US 8,491,525
App. No.
11/942,080
Granted
Jul 23, 2013
Kind
B2
Abstract

A needleless fluid delivery system for delivering therapeutic fluids to treatment sites within a patient. The fluid delivery system can include an automated injector source and a needleless access device. The access device can include a delivery scope and a treatment specific applicator. The automated injector source, delivery scope and applicator can be operably coupled with quick-connect style fittings so as to allow for quick replacement and maintenance of used or damaged components. The automated injector source can include a hands-free input mechanism allowing a medical professional to use both hands in manipulating the delivery scope and needleless applicator at the same time an injection is desired. The delivery scope and needleless applicator can comprise flexible or rigid lengths of tubing based on the accessibility of the treatment site. The needleless delivery system can include an imaging system for precisely position the applicator with respect to the treatment location.

Claims (10)

1. A needleless fluid delivery system comprising:

an automated injector source including a user interface, a controller having a receiving element and a connector member; and

an applicator including a scope portion and a delivery portion, the scope portion adapted to attach to the connector member such that a pressurized fluid from the automated injector source can be delivered to a treatment site through a delivery lumen defined within the applicator, wherein the applicator includes a communication member for communicating an applicator configuration directly to the receiving element, wherein the controller preconfigures the automated injector source for standard operating conditions consistent with the applicator configuration of the applicator.

2. The needleless fluid delivery system of claim 1 , wherein the user interface included an input means selected from the group consisting of: a foot pedal and a touch screen.

3. The needleless fluid delivery system of claim 1 , wherein the applicator is selected from the group consisting of: a male urethra applicator, a prostate applicator, a bladder applicator, a female bladder/urethra applicator and a ureter/kidney applicator.

4. The needleless fluid delivery system of claim 1 , wherein the communication member is selected from the group consisting of: a microchip and a RFID tag.

5. The needleless fluid delivery system of claim 1 , wherein the scope portion includes a flexible scope and a supply connector adapted to operably attach to the connector member.

6. The needleless fluid delivery system of claim 5 , wherein the delivery portion includes a flexible tube that is steerable by the flexible scope.

7. The needleless fluid delivery system of claim 6 , wherein the flexible tube includes a tube vacuum lumen and a tube delivery lumen and an applicator head is slidably positioned over the flexible tube such that an applicator vacuum lumen is operably connected to the tube vacuum lumen and an applicator delivery lumen is operably connected to the tube delivery lumen wherein a vacuum source in the automated injector proximates tissue against a treatment end of the applicator head such that an injection fluid can be delivered through the applicator delivery lumen at the treatment end.

8. The needleless fluid delivery system of claim 6 , wherein an applicator head is slidably advanced through the flexible tube, the applicator head including an applicator vacuum lumen and an applicator delivery lumen such that the applicator head can be advanced into a working channel in the flexible tube such that a vacuum source in the automated injector proximates tissue within the working channel wherein an injection fluid can be delivered through the applicator delivery lumen at the working channel.

Assignments (17)
RELEASE OF SECURITY INTEREST Recorded Apr 26, 2024
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACTIENT PHARMACEUTICALS LLC; ASTORA WOMEN’S HEALTH HOLDINGS, LLC; ASTORA WOMEN’S HEALTH LLC; AUXILIUM PHARMACEUTICALS, LLC; AUXILIUM US HOLDINGS, LLC; BIOSPECIFICS TECHNOLOGIES CORP.; BIOSPECIFICS TECHNOLOGIES LLC; DAVA INTERNATIONAL, LLC; DAVA PHARMACEUTICALS, LLC; ENDO GENERIC HOLDINGS, INC. (FORMERLY KNOWN AS PAR PHARMACEUTICALS COMPANIES, INC.); ENDO PHARMACEUTICALS INC.; ENDO PHARMACEUTICALS SOLUTIONS INC. (FORMERLY KNOWN AS INDEVUS PHARMACEUTICALS, INC.); GENERICS BIDCO I, LLC; GENERICS INTERNATIONAL (US), INC.; PAR PHARMACEUTICAL, INC.; PAR STERILE PRODUCTS, LLC (FORMERLY KNOWN AS JHP PHARMACEUTICALS, LLC); QUARTZ SPECIALTY PHARMACEUTICALS, LLC; SLATE PHARMACEUTICALS, LLC; VINTAGE PHARMACEUTICALS, LLC
Reel/Frame 067239/0795 →
RELEASE OF SECURITY INTEREST Recorded Apr 25, 2024
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACTIENT PHARMACEUTICALS LLC; ASTORA WOMEN’S HEALTH LLC; AUXILIUM PHARMACEUTICALS, LLC; AUXILIUM US HOLDINGS, LLC; BIOSPECIFICS TECHNOLOGIES CORP.; BIOSPECIFICS TECHNOLOGIES LLC; DAVA INTERNATIONAL, LLC; DAVA PHARMACEUTICALS, LLC; ENDO PHARMACEUTICALS INC.; ENDO PHARMACEUTICALS SOLUTIONS INC. (FORMERLY KNOWN AS INDEVUS PHARMACEUTICALS, INC.); GENERICS BIDCO I, LLC; GENERICS INTERNATIONAL (US), INC.; PAR PHARMACEUTICAL, INC.; PAR PHARMACEUTICAL COMPANIES, INC.; PAR STERILE PRODUCTS, LLC (FORMERLY KNOWN AS JHP PHARMACEUTICALS, LLC); QUARTZ SPECIALTY PHARMACEUTICALS, LLC; SLATE PHARMACEUTICALS, LLC; VINTAGE PHARMACEUTICALS, LLC
Reel/Frame 067239/0491 →
RELEASE OF SECURITY INTEREST Recorded Apr 25, 2024
From: WILMINGTON TRUST, NATIONAL ASSOCIATION
To: ACTIENT PHARMACEUTICALS LLC; ASTORA WOMEN’S HEALTH LLC; AUXILIUM PHARMACEUTICALS, LLC; AUXILIUM US HOLDINGS, LLC; BIOSPECIFICS TECHNOLOGIES CORP.; BIOSPECIFICS TECHNOLOGIES LLC; DAVA INTERNATIONAL, LLC; DAVA PHARMACEUTICALS, LLC; ENDO PHARMACEUTICALS INC.; ENDO PHARMACEUTICALS SOLUTIONS INC. (FORMERLY KNOWN AS INDEVUS PHARMACEUTICALS, INC.); GENERICS BIDCO I, LLC; GENERICS INTERNATIONAL (US), INC.; PAR PHARMACEUTICAL, INC.; PAR PHARMACEUTICAL COMPANIES, INC.; PAR STERILE PRODUCTS, LLC (FORMERLY KNOWN AS JHP PHARMACEUTICALS, LLC); QUARTZ SPECIALTY PHARMACEUTICALS, LLC; SLATE PHARMACEUTICALS, LLC; VINTAGE PHARMACEUTICALS, LLC
Reel/Frame 067239/0542 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Sep 17, 2021
From: ASTORA WOMEN'S HEALTH LLC; ENDO PHARMACEUTICALS SOLUTIONS INC.; ENDO PHARMACEUTICALS INC.; PAR PHARMACEUTICAL, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 057538/0978 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Apr 6, 2021
From: BIOSPECIFICS TECHNOLOGIES LLC; PAR PHARMACEUTICAL, INC.; AUXILIUM US HOLDINGS, LLC; ASTORA WOMEN'S HEALTH, LLC; ENDO PHARMACEUTICALS SOLUTIONS INC.; ENDO PHARMACEUTICALS, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 055846/0246 →
CONFIRMATORY GRANT OF SECURITY INTEREST IN UNITED STATES PATENTS Recorded Apr 6, 2021
From: BIOSPECIFICS TECHNOLOGIES LLC; PAR PHARMACEUTICAL, INC.; AUXILIUM US HOLDINGS, LLC; ASTORA WOMEN'S HEALTH, LLC; ENDO PHARMACEUTICALS SOLUTIONS INC.; ENDO PHARMACEUTICALS, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION
Reel/Frame 055845/0618 →
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2017
From: DEUTSCHE BANK AG NEW YORK BRANCH
To: ENDO PHARMACEUTICALS, INC.; ENDO PHARMACEUTICALS SOLUTIONS, INC.; ASTORA WOMEN'S HEALTH HOLDINGS, LLC
Reel/Frame 042362/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2017
From: AMS RESEARCH, LLC
To: AMERICAN MEDICAL SYSTEMS, LLC
Reel/Frame 042092/0417 →
CHANGE OF NAME Recorded Apr 21, 2017
From: ASTORA WOMEN'S HEALTH, INC.
To: ASTORA WOMEN'S HEALTH HOLDINGS, LLC
Reel/Frame 042310/0682 →
CHANGE OF NAME Recorded Apr 21, 2017
From: AMERICAN MEDICAL SYSTEMS HOLDINGS, INC.
To: ASTORA WOMEN'S HEALTH, INC.
Reel/Frame 042310/0640 →
CHANGE OF NAME Recorded Apr 21, 2017
From: AMS RESEARCH CORPORATION
To: AMS RESEARCH, LLC
Reel/Frame 042310/0335 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2017
From: AMERICAN MEDICAL SYSTEMS, LLC
To: AMERICAN MEDICAL SYSTEMS HOLDINGS, INC.
Reel/Frame 042092/0559 →
GRANT OF SECURITY INTEREST IN PATENTS Recorded Mar 20, 2014
From: ENDO PHARMACEUTICALS SOLUTIONS, INC.; ENDO PHARMACEUTICALS, INC.; AMS RESEARCH CORPORATION; AMERICAN MEDICAL SYSTEMS, INC.; LASERSCOPE
To: DEUTSCHE BANK AG NEW YORK BRANCH, AS COLLATERAL AGENT
Reel/Frame 032491/0440 →
RELEASE OF PATENT SECURITY INTEREST Recorded Mar 3, 2014
From: MORGAN STANLEY SENIOR FUNDING, INC., AS ADMINISTRATIVE AGENT
To: AMS RESEARCH CORPORATION
Reel/Frame 032380/0053 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2011
From: ROYCHOWDHURY, SURANJAN; COPA, VINCENT G.; HAUSCHILD, SIDNEY F.
To: AMS RESEARCH CORPORATION
Reel/Frame 027369/0570 →
SECURITY AGREEMENT Recorded Jul 22, 2011
From: AMS RESEARCH CORPORATION
To: MORGAN STANLEY SENIOR FUNDING, INC., AS ADMINISTRATIVE AGENT
Reel/Frame 026632/0535 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2008
From: ROYCHOWDHURY, SURANJAN; COPA, VINCENT G.
To: AMS RESEARCH CORPORATION
Reel/Frame 021074/0679 →