IP Library › Patent Application 11944337
Patent Application
App. No. 11/944,337

METHOD FOR TREATING NEOVASCULARIZATION AND INTRAVITREAL IMPLANTS

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Quick Facts
Patent No.
US None
App. No.
11/944,337
Abstract

Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a bioerodible drug delivery system comprising an immunosuppressive agent and a bioerodible polymer.

Claims (6)

1 . (canceled)

2 . A method for treating neovascularization in an eye of an individual, the method comprising implanting in the vitreous of an eye prone to neovascularization an intravitreal, biodegradable drug delivery system comprising an immunosuppressive agent and a polylactic acid polyglycolic acid (PLGA) copolymer.

3 . The method of claim 2 , wherein said immunosuppressive agent is a steroid.

4 . The method of claim 3 wherein the steroid is dexamethasone.

5 . The method of claim 3 , wherein the steroid comprises about 10% to 90% of the weight of the intravitreal, bioerodible drug delivery system.

6 . The method of claim 5 , wherein the steroid comprises about 50% to about 80% by weight of the drug delivery system.