IP Library Granted Patent US 8,435,234
Granted Patent B2
US 8,435,234 · App. 11/983,334 · Granted May 7, 2013

Method and apparatus for monitoring and controlling laser-induced tissue treatment

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Quick Facts
Patent No.
US 8,435,234
App. No.
11/983,334
Granted
May 7, 2013
Kind
B2
Abstract

The present invention relates to a method and apparatus for using an imaging detector to image an optical pattern created by illumination of a viscous material that is applied to the skin. The viscous material forms a detectable pattern that can be imaged by the imaging detector. In some examples, the viscous material is reflective and allows reflection from an illumination source to create an optical pattern on the imaging detector. In other cases, the variation in thickness of an absorbing or scattering viscous substance can be imaged by the detector. Polarized illumination and detection can be used to enhance the response.

Claims (39)

1. A method of dermatological treatment, the method comprising:

applying a viscous material to a region of skin tissue to be treated;

emitting treatment energy from a handpiece towards the region of skin tissue to effect tissue treatment, the treatment energy comprising a variable operational parameter that affects a dosage of the tissue treatment;

moving the handpiece across the region of skin tissue, the movement of the handpiece comprising a variable positional parameter that affects the dosage of the tissue treatment;

forming an imageable pattern comprising a plurality of ridges of the viscous material that are produced as the viscous material conforms under the movement of the handpiece over the viscous material and across the region of skin tissue;

directing illumination toward the ridges of the viscous material in the imageable pattern;

imaging in real-time a pattern of the illumination that is reflected from the ridges of the viscous material;

determining the variation in the positional parameter from the imaged pattern of the illumination; and

controllably adjusting in real-time the operational parameter in response to the variation in the positional parameter determined from the imaged pattern of the illumination,

wherein the viscous material has a viscosity greater than 2*10 3 cP such that the shape of the ridges is retained in the viscous material while the pattern of illumination is detected in real-time.

2. The method of claim 1 , wherein the viscous material is thixotropic.

3. The method of claim 1 , wherein the viscous material is shear thinning.

4. The method of claim 1 , wherein the viscous material has a viscosity greater than 8*10 3 cP.

5. The method of claim 1 , wherein the viscous material has a viscosity in a range of about 2*10 3 cP to about 1*10 8 cP.

6. The method of claim 1 , wherein the viscous material has a viscosity in a range of about 1*10 4 cP to about 1*10 5 cP.

7. The method of claim 1 , wherein the viscous material comprises petroleum jelly.

8. The method of claim 1 , wherein the treatment energy is optical treatment energy and the viscous material is optically transparent to the treatment energy.

9. The method of claim 1 , wherein the viscous material is chosen from a group consisting of petroleum jelly, ointment, gel, and moisturizing cleanser.

10. The method of claim 1 , wherein the viscous material comprises a mixture of water and a copolymer of vinyl acetate and vinylpyrrolidone.

11. The method of claim 1 , wherein a thickness of the applied viscous material is in a range of about 0.03 mm to about 0.5 mm.

12. The method of claim 1 , wherein a thickness of the applied viscous material is about 0.1 mm.

13. The method of claim 1 , wherein the viscous material has a viscosity index in a range of about 10 to about 45.

14. The method of claim 1 , wherein the viscous material has a viscosity index in a range of about 50 to about 150.

15. The method of claim 1 , wherein the viscous material has a viscosity index in a range of about 70 to about 100.

16. The method of claim 1 , wherein moving the handpiece comprises:

rolling the handpiece across the region of skin tissue on two or more rollers to form the ridges in the imageable patter.

17. The method of claim 1 , wherein moving the handpiece comprises:

sliding the handpiece across the region of skin tissue on two or more elongated runners to form the ridges in the imageable pattern.

18. The method of claim 1 , further comprising:

cooling a surface of the viscous material.

19. The method of claim 1 , wherein the dermatological treatment is a cosmetic treatment.

20. The method of claim 19 , wherein the dermatological treatment is a cosmetic treatment of wrinkles.

21. The method of claim 1 , wherein a detector detects in real-time the pattern of the illumination that is reflected from the ridges in the imageable pattern in the viscous material, and the detector comprises an optical mouse package.

22. The method of claim 1 , wherein emitting treatment energy comprises:

delivering a fractional pattern of treatment energy.

23. The method of claim 22 , wherein the operational parameter comprises at least one of treatment zone density, pulse duration, pulse timing, treatment zone size, and treatment power.

24. The method of claim 22 , wherein the treatment energy is delivered with spot diameters of less than about 500 μm.

25. The method of claim 1 wherein the ridges project from a surface of the region of skin tissue.

26. The method of claim 1 wherein the ridges project toward the handpiece.

Assignments (19)
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH HEALTH AMERICAS, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.
Reel/Frame 073637/0126 →
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
Reel/Frame 073654/0242 →
RELEASE OF SECURITY INTEREST Recorded Nov 20, 2025
From: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
To: BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; BAUSCH HEALTH IRELAND LIMITED; SOLTA MEDICAL IRELAND LIMITED
Reel/Frame 073654/0300 →
U.S. PATENT SECURITY AGREEMENT Recorded Jun 13, 2025
From: MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; BAUSCH HEALTH US, LLC (F/K/A VALEANT PHARMACEUTICALS NORTH AMERICA LLC); PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SANTARUS, INC.; BAUSCH HEALTH AMERICAS, INC.; SOLTA MEDICAL, INC.
To: THE BANK OF NEW YORK MELLON
Reel/Frame 071564/0463 →
U.S. PATENT SECURITY AGREEMENT Recorded Jun 13, 2025
From: MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; BAUSCH HEALTH US, LLC (F/K/A VALEANT PHARMACEUTICALS NORTH AMERICA LLC); PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SANTARUS, INC.; BAUSCH HEALTH AMERICAS, INC.; SOLTA MEDICAL, INC.
To: JPMORGAN CHASE BANK, N.A.
Reel/Frame 071566/0200 →
SECURITY AGREEMENT (SECOND LIEN) Recorded Oct 5, 2022
From: BAUSCH HEALTH US, LLC; BAUSCH HEALTH AMERICAS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; SOLTA MEDICAL, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 061606/0468 →
SECURITY AGREEMENT (FIRST LIEN) Recorded Oct 4, 2022
From: BAUSCH HEALTH US, LLC; BAUSCH HEALTH AMERICAS, INC.; MEDICIS PHARMACEUTICAL CORPORATION; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; SOLTA MEDICAL, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 061595/0066 →
SECURITY INTEREST Recorded Jun 13, 2022
From: BAUSCH HEALTH COMPANIES INC.; BAUSCH HEALTH, CANADA INC.; BAUSCH HEALTH IRELAND LIMITED; SOLTA MEDICAL IRELAND LIMITED
To: THE BANK OF NEW YORK MELLON
Reel/Frame 060346/0705 →
SECURITY AGREEMENT Recorded Feb 10, 2022
From: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
To: THE BANK OF NEW YORK MELLON
Reel/Frame 059121/0001 →
SECURITY INTEREST Recorded Jun 8, 2021
From: BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.; BAUSCH HEALTH AMERICAS, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 056811/0814 →
MERGER Recorded May 14, 2021
From: RELIANT TECHNOLOGIES, LLC
To: SOLTA MEDICAL, INC.
Reel/Frame 056244/0936 →
MERGER Recorded May 12, 2021
From: RELIANT TECHNOLOGIES, INC.
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 056218/0067 →
SECURITY INTEREST Recorded Mar 11, 2019
From: BAUSCH HEALTH AMERICAS, INC.; BAUSCH & LOMB INCORPORATED; BAUSCH HEALTH US, LLC; SOLTA MEDICAL, INC.; MEDICIS PHARMACEUTICAL CORPORATION; SALIX PHARMACEUTICALS, INC.; SALIX PHARMACEUTICALS, LTD.; SANTARUS, INC.; ORAPHARMA, INC.; PRECISION DERMATOLOGY, INC.
To: THE BANK OF NEW YORK MELLON, AS NOTES COLLATERAL AGENT
Reel/Frame 048556/0758 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 27, 2014
From: SILICON VALLEY BANK
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 032125/0810 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Jan 24, 2014
From: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
To: RELIANT TECHNOLOGIES, LLC
Reel/Frame 032126/0708 →
SHORT-FORM PATENT SECURITY AGREEMENT Recorded Nov 19, 2013
From: RELIANT TECHNOLOGIES, LLC
To: CAPITAL ROYALTY PARTNERS II L.P.; CAPITAL ROYALTY PARTNERS II - PARALLEL FUND "A" L.P.; PARALLEL INVESTMENT OPPORTUNITIES PARTNERS II L.P.
Reel/Frame 031674/0527 →
SECURITY INTEREST - MEZZANINE LOAN Recorded Apr 18, 2013
From: RELIANT TECHNOLOGIES, LLC
To: SILICON VALLEY BANK
Reel/Frame 030248/0256 →
SECURITY AGREEMENT Recorded Jun 16, 2009
From: RELIANT TECHNOLOGIES, LLC
To: SILICON VALLEY BANK
Reel/Frame 022824/0847 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2007
From: CHAN, KIN F.; DEBENEDICTIS, LEONARD C.
To: RELIANT TECHNOLOGIES, INC.
Reel/Frame 020150/0679 →