IP Library Granted Patent US 8,032,197
Granted Patent B2
US 8,032,197 · App. 11/999,634 · Granted Oct 4, 2011

Method of analyzing for at least one disease or condition marker

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,032,197
App. No.
11/999,634
Granted
Oct 4, 2011
Kind
B2
Abstract

A method of using a diffusion-based, continuous-monitoring system to analyze for a disease or condition includes creating a diffusion channel in an area of skin. The diffusion channel is maintained for a desired duration. The level of the disease marker(s) is continuously monitored for the desired duration via a diffusion-based, continuous-monitoring device. The levels of the at least one disease marker at the area of skin are analyzed to determine if the disease or condition associated with the at least one disease marker is present.

Claims (28)

1. A method of using a diffusion-based, continuous-monitoring system to analyze for a state of a disease or condition, the method comprising the acts of:

creating at least one diffusion channel in an area of skin;

applying a hydrogel on the skin, the hydrogel being configured to enhance diffusion from the at least one diffusion channel;

maintaining the at least one diffusion channel for a desired duration;

continuously monitoring the level of at least one disease/condition marker for the desired duration via a diffusion-based, continuous-monitoring device; and

analyzing the levels of the at least one disease/condition marker at the area of skin to determine if the disease or condition associated with the at least one disease/condition marker is present.

2. The method of claim 1 wherein the at least one diffusion channel is a plurality of diffusion channels.

3. The method of claim 1 wherein the desired duration is a continuous time period of at least approximately 8 hours.

4. The method of claim 1 wherein the desired duration is a continuous time period of at least approximately 24 hours.

5. The method of claim 1 wherein the diffusion-based, continuous-monitoring system is an electrochemical-monitoring system.

6. The method of claim 1 wherein the diffusion-based, continuous-monitoring system is an optical-monitoring system.

7. The method of claim 1 further including storing the level of the at least one disease marker.

8. The method of claim 1 further including positioning the diffusion-based, continuous-monitoring device in communication with the hydrogel or liquid.

9. The method of claim 1 wherein the continuously monitoring is of the level of blood urea nitrogen and/or creatinine, and the levels of the blood urea nitrogen and/or creatinine at the area of skin is being analyzed to determine if kidney disease is present.

10. The method of claim 9 wherein the level of blood urea nitrogen is continuously monitored.

11. The method of claim 9 wherein the level of creatinine is continuously monitored.

12. The method of claim 9 wherein at least the levels of blood urea nitrogen and creatinine are continuously monitored.

13. A method of using a diffusion-based, continuous-monitoring system to analyze for a state of at least one disease or condition, the method comprising the acts of:

providing a diffusion-based, continuous-monitoring device, the device including a communications interface that is adapted to connect with a receiving module via a communications link;

creating at least one diffusion channel in an area of skin via a channel-creating mechanism, the channel-creating mechanism being separate and distinct from the diffusion-based, continuous-monitoring device;

applying a hydrogel on the skin, the hydrogel being configured to enhance diffusion from the at least one diffusion channel

maintaining the at least one diffusion channel for a desired duration;

continuously monitoring the level of at least one disease or condition marker for the desired duration via the diffusion-based, continuous-monitoring device; and

analyzing the levels of the at least one disease or condition marker at the area of skin to determine if the disease or condition associated with the at least one disease or condition marker is present.

14. The method of claim 13 further including transmitting information directed to the levels of the at least one disease or condition marker to the receiving module via the communications link.

15. The method of claim 14 further including receiving instructions from the receiving module via the communications link.

16. The method of claim 14 wherein the transmitting of information occurs at intervals between 5 minutes and 4 hours.

17. The method of claim 13 further including storing the levels the at least one disease or condition marker.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2016
From: BAYER HEALTHCARE LLC
To: ASCENSIA DIABETES CARE HOLDINGS AG
Reel/Frame 037880/0604 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 020253 FRAME: 0735. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 20, 2015
From: REBEC, MIHAILO V.
To: BAYER HEALTHCARE LLC
Reel/Frame 037337/0731 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 6, 2007
From: REBEC, MIHAILO V.
To: BAYER HEALTHCARE LLC
Reel/Frame 020253/0735 →