IP Library Granted Patent US 7,592,498
Granted Patent B2
US 7,592,498 · App. 12/002,582 · Granted Sep 22, 2009

Metathesis catalysts

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Quick Facts
Patent No.
US 7,592,498
App. No.
12/002,582
Granted
Sep 22, 2009
Kind
B2
Abstract

The invention relates to polymeric transition metal catalysts, to processes for preparing them, to intermediates and also to the use of the transition metal catalysts as catalysts in organic reactions, in particular in olefin metathesis reactions.

Claims (44)

1. Process for preparing polymeric compounds, characterized in that compounds of the formula (IIIa) and/or (IIIb)

where

R 1 is cyclic, straight-chain or branched C 1 -C 20 -alkyl or C 5 -C 24 -aryl;

L is an N-heterocyclic carbene ligand of the formula (II)

where the direction of the arrow is intended to represent carbene electrons and the bond to M and where

B is 1,2-ethanediyl or 1,2-ethenediyl radical which is optionally mono- or disubstituted by C 1 -C 4 -alkyl, C 6 -C 15 -arylalkyl, or C 5 -C 14 -aryl; and

X 1 and X 2 are the same or different and are each chlorine, bromine or iodine,

and

ortho-arylene is an ortho-phenylene or ortho-naphthylene radical and said radicals may also be substituted by one, two, three or four radicals per cycle which are selected from the group of C 1 -C 4 -alkyl, C 5 -C 14 -aryl and C 1 -C 4 -alkoxy and

Ar is C 5 -C 14 -aryl and

R 12 , R 13 and R 14 are each independently C 1 -C 8 -alkyl or C 5 -C 14 -aryl

are reacted

with at least one compound of the formula (IV)

where

R 1 is defined above with respect to formula (IIIa) and/or formula (IIIb);

R 2 , R 3 and R 4 are each independently hydrogen, C 1 -C 20 -alkyl, C 5 -C 24 -aryl, halogen, C 1 -C 4 -fluoroalkyl, C 1 -C 4 -alkoxy, C 5 -C 14 -aryloxy, (C 1 -C 8 -alkyl)OCO—, (C 1 -C 8 -alkyl)CO 2 —, (C 5 -C 14 -aryl)OCO— or (C 5 -C 14 -aryl)CO 2 — and/or

in each case two radicals in an ortho-arrangement to one another from the group of R 2 , R 3 and R 4 are part of a cyclic system which consists of a carbon framework having 5 to 22 carbon atoms, one or more carbon atoms of the cyclic system optionally being replaced by heteroatoms from the group of sulphur, oxygen or nitrogen, and the cyclic system also being optionally mono- or polysubstituted by radicals selected from the group of halogen, C 1 -C 4 -fluoroalkyl, (C 1 -C 4 -alkyl)OCO—, (C 1 -C 8 -alkyl)CO 2 —, (C 6 -C 10 -aryl)OCO— or (C 5 -C 14 -aryl)CO 2 —;

A is oxygen, sulphur, sulphoxyl, sulphonyl or CR 8 R 9 where R 8 and R 9 are each independently hydrogen or C 1 -C 4 -alkyl and

D is C 1 -C 8 -alkylene, [(C 1 -C 8 -alkylene)-O—] n where n=1 to 12, (C 1 -C 8 -alkylene)CO 2 —, (C 1 -C 8 -alkylene)-OCO—(C 1 -C 8 -alkylene), (C 1 -C 8 -alkylene)CO 2 —(C 1 -C 8 -alkylene), (C 1 -C 8 -alkylene)CONR 10 —, (C 1 -C 8 -alkylene)NR 10 CO—, (C 1 -C 8 -alkylene)CONR 10 —(C 1 -C 8 -alkylene) or (C 1 -C 8 -alkylene)NR 10 CO—(C 1 -C 8 -alkylene) where R 10 is hydrogen or C 1 -C 4 -alkyl.

2. Process according to claim 1 , characterized in that the reaction is also effected with at least one compound of the formula (V),

where

A has the same definition and fulfils the same conditions as specified under the formula (IV) in claim 1 ; and

R 11 is C 1 -C 8 -alkyl, [(C 1 -C 8 -alkylene)-O—] n —(C 1 -C 8 -alkyl) where n=1 to 12, (C 1 -C 8 -alkylene)CO 2 —(C 1 -C 8 -alkyl), (C 1 -C 8 -alkylene)-OCO—(C 1 -C 8 -alkyl), (C 1 -C 8 -alkylene)-OCO—(C 5 -C 14 -aryl), (C 1 -C 8 -alkylene)CO 2 —(C 5 -C 14 -aryl), (C 1 -C 8 -alkylene)CONR 10 —(C 1 -C 8 -alkyl), (C 1 -C 8 -alkylene)NR 10 CO—(C 1 -C 8 -alkyl), (C 1 -C 8 -alkylene)CONR 10 —(C 5 -C 14 -aryl) or (C 1 -C 8 -alkylene)NR 10 CO—(C 5 -C 14 -aryl) where R 10 is hydrogen or C 1 -C 4 -alkyl.

3. Process according to claim 1 , wherein the reaction is also effected with one or more further olefins which can be polymerized by ring-opening metathesis.

4. Process according to claim 1 , wherein compound of formula (IV) is 7-Oxa-2-norborn-2-en-5-ylmethyl 2-isopropoxy-3-ethenylphenyl ether.

5. Process for preparing olefins by catalytic olefin metathesis comprising providing as catalysts to the metathesis reaction polymeric compounds, wherein said polymeric compounds are prepared by providing compounds of the formula (IIIa) and/or (IIIb)

where

R 1 is cyclic, straight-chain or branched C 1 -C 20 -alkyl or C 5 -C 24 -aryl;

L is an N-heterocyclic carbene ligand of the formula (II)

where the direction of the arrow is intended to represent carbene electrons and the bond to M and where

B is 1,2-ethanediyl or 1,2-ethenediyl radical which is optionally mono- or disubstituted by C 1 -C 4 alkyl, C 6 -C 15 -arylalkyl, C 5 -C 14 -aryl; and

X 1 and X 2 are the same or different and are each chlorine, bromine or iodine, and

ortho-arylene is an ortho-phenylene or ortho-naphthylene radical and said radicals may also be substituted by one, two, three or four radicals per cycle which are selected from the group of C 1 -C 4 -alkyl, C 5 -C 14 -aryl and C 1 -C 4 -alkoxy and

Ar is C 5 -C 14 -aryl and

R 12 , R 13 and R 14 are each independently C 1 -C 8 -alkyl or C 5 -C 14 -aryl

and reacting compounds of formula (IIIa) and (IIIb)

with at least one compound of the formula (IV)

where

R 1 is defined above with respect to formula (IIIa) and/or formula (IIIb);

R 2 , R 3 and R 4 are each independently hydrogen, C 1 -C 20 -alkyl, C 5 -C 24 -aryl, halogen, C 1 -C 4 -fluoroalkyl, C 1 -C 4 -alkoxy, C 5 -C 14 -aryloxy, (C 1 -C 8 -alkyl)OCO—, (C 1 -C 8 -alkyl)CO 2 —, (C 5 -C 14 -aryl)OCO— or (C 5 -C 14 -aryl)CO 2 — and/or

in each case two radicals in an ortho-arrangement to one another from the group of R 2 , R 3 and R 4 are part of a cyclic system which consists of a carbon framework having 5 to 22 carbon atoms, one or more carbon atoms of the cyclic system optionally being replaced by heteroatoms from the group of sulphur, oxygen or nitrogen, and the cyclic system also being optionally mono- or polysubstituted by radicals selected from the group of halogen, C 1 -C 4 -fluoroalkyl, (C 1 -C 4 -alkyl)OCO—, (C 1 -C 8 -alkyl)CO 2 —, (C 6 -C 10 aryl)OCO— or (C 5 -C 14 -aryl)CO 2 —;

A is oxygen, sulphur, sulphoxyl, sulphonyl or CR 8 R 9 where R 8 and R 9 are each independently hydrogen or C 1 -C 4 -alkyl and

D is C 1 -C 8 -alkylene, [(C 1 -C 8 -alkylene)-O—] n where n=1 to 12, (C 1 -C 8 -alkylene)CO 2 —, (C 1 -C 8 -alkylene)-OCO—(C 1 -C 8 -alkylene), (C 1 -C 8 -alkylene)CO 2 —(C 1 -C 8 -alkylene), (C 1 -C 8 -alkylene)CONR 10 —, (C 1 -C 8 -alkylene)NR 10 CO—, (C 1 -C 8 -alkylene)CONR 10 —(C 1 -C 8 -alkylene) or (C 1 -C 8 -alkylene)NR 10 CO—(C 1 -C 8 -alkylene) where R 10 is hydrogen or C 1 -C 4 -alkyl.

6. Process according to claim 5 , wherein the catalysts are removed from the catalytic reaction mixtures and reused for the preparation of olefins by catalytic olefin metathesis.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2016
From: LANXESS DEUTSCHLAND GMBH
To: ARLANXEO DEUTSCHLAND GMBH
Reel/Frame 039753/0760 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2008
From: BLECHERT, SIEGFRIED; CONNON, STEPHEN
To: BAYER AKTIENGESELLSCHAFT
Reel/Frame 021734/0529 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2008
From: BAYER AG
To: LANXESS DEUTSCHLAND GMBH
Reel/Frame 021734/0958 →