IP Library Patent Application 12005833
Patent Application
App. No. 12/005,833

Modulation of pathogenicity

Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US None
App. No.
12/005,833
Abstract

The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R 1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R 2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A 1 and A 2 each independently represent an optionally substituted C 1 -C 20 -alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR 4 , CO, CO 2 , CS, SO or SO 2 X is selected from the group consisting of S, O, N, NR 4 , SO or SO 2 ;

Claims (6)

1 . A compound

or a pharmaceutically acceptable salt or physiologically acceptable derivative thereof.

2 . A method for inhibiting the production of a virulence factor comprising contact with a compound of claim 1 .

3 . The method of claim 2 for the treatment or prevention of bacterial damage or disease.

4 . The method of claim 3 wherein the bacteria is Pseudomonas aeruginosa or Burkholderia cepacia.

5 . A composition for inhibiting biofilm formation comprising a compound of claim 1 .

Assignments (2)
QUITCLAIM DEED Recorded Jan 7, 2009
From: LV ADMINISTRATIVE SERVICES, INC.
To: QUONOVA, LLC
Reel/Frame 022062/0439 →
AMENDMENT TO INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Jul 8, 2008
From: XL TECHGROUP, INC.; DXTECH, LLC; PETROALGAE, LLC; QUONOVA, LLC
To: LV ADMINISTRATIVE SERVICES, INC.
Reel/Frame 021205/0643 →