IP Library › Granted Patent US 7,569,697
Granted Patent B2
US 7,569,697 · App. 12/006,845 · Granted Aug 4, 2009

Benzimidazole compound crystal

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Quick Facts
Patent No.
US 7,569,697
App. No.
12/006,845
Granted
Aug 4, 2009
Kind
B2
Abstract

A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl],sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.

Claims (4)

1. A method for manufacturing a preparation for oral administration, which comprises:

formulating a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof and a pharmaceutically acceptable carrier into a first composition; and

subsequently forming the preparation for oral administration.

2. The method according to claim 1 wherein the X-ray powder diffraction analysis pattern of the crystal has characteristic peaks at the interplanar spacings (d) of 11.68, 6.77, 5.84, 5.73, 4.43, 4.09, 3.94, 3.89, 3.69, 3.41, and 3.11 Angstrom.