IP Library Granted Patent US 8,529,426
Granted Patent B2
US 8,529,426 · App. 12/012,220 · Granted Sep 10, 2013

Ionizing-radiation-responsive compositions, methods, and systems

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Quick Facts
Patent No.
US 8,529,426
App. No.
12/012,220
Granted
Sep 10, 2013
Kind
B2
Abstract

A method, composition and system respond to ionizing radiation to adjust biological activity. In some approaches the ionizing radiation is X-ray or extreme ultraviolet radiation that produces luminescent responses that induce biologically active responses.

Claims (27)

1. A method, comprising:

identifying a first process that at least partially converts ionizing radiation to an amount of optical energy;

identifying a second process that at least partially converts the amount of optical energy to biological activity;

responsive to the identifying a first process and the identifying a second process, determining an amount of ionizing radiation whereby a selected amount of biological activity is produced by a combination of the first process and the second process;

irradiating at least one region with the determined amount of ionizing radiation;

detecting an amount of ionizing radiation that is transmitted or forward scattered through at least a portion of the at least one region; and

determining an amount of biological activity corresponding to the detected amount of ionizing radiation.

2. The method of claim 1 , further comprising:

adjusting the irradiating to obtain the selected amount of biological activity.

3. A system, comprising:

means for identifying a first process that at least partially converts ionizing radiation to an amount of optical energy;

means for identifying a second process that at least partially converts the amount of optical energy to biological activity;

means, responsive to the means for identifying a first process and the means for identifying a second process, for determining an amount of ionizing radiation whereby a selected amount of biological activity is produced by a combination of the first process and the second process;

means for irradiating at least one region with the determined amount of ionizing radiation;

means for detecting an amount of ionizing radiation that is transmitted or forward scattered through at least a portion of the at least one region; and

means for determining an amount of biological activity corresponding to the detected amount of ionizing radiation.

4. The system of claim 3 , further comprising:

means for adjusting the irradiating to obtain the selected amount of biological activity.

5. A system, comprising:

circuitry for identifying a first process that at least partially converts ionizing radiation to an amount of optical energy;

circuitry for identifying a second process that at least partially converts the amount of optical energy to biological activity;

circuitry, responsive to the circuitry for identifying a first process and the circuitry for identifying a second process, for determining an amount of ionizing radiation whereby a selected amount of biological activity is produced by a combination of the first process and the second process;

circuitry for irradiating at least one region with the determined amount of ionizing radiation;

circuitry for detecting an amount of ionizing radiation that is transmitted or forward scattered through at least a portion of the at least one region; and

circuitry for determining an amount of biological activity corresponding to the detected amount of ionizing radiation.

6. The system of claim 5 , further comprising:

circuitry for adjusting the irradiating to obtain the selected amount of biological activity.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 15, 2016
From: THE INVENTION SCIENCE FUND I LLC
To: GEARBOX, LLC
Reel/Frame 037540/0134 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 24, 2013
From: SEARETE LLC
To: THE INVENTION SCIENCE FUND I LLC
Reel/Frame 030481/0664 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2008
From: BOYDEN, EDWARD S.; HYDE, RODERICK A.; ISHIKAWA, MURIEL Y.; JUNG, EDWARD K.Y.; MYHRVOLD, NATHAN P.; TEGREENE, CLARENCE T.; WEAVER, THOMAS A.; WHITMER, CHARLES; WOOD, JR., LOWELL L.; WOOD, VICTORIA Y.H.
To: SEARETE LLC
Reel/Frame 020868/0542 →