IP Library Granted Patent US 8,591,503
Granted Patent B2
US 8,591,503 · App. 12/018,403 · Granted Nov 26, 2013

Cryotherapy probe

Inventors: Peter J. Littrup (Bloomfield Hills, MI); Alexei V. Babkin (Albuquerque, NM); Robert V. Duncan (Tijeras, NM); Pramod Kerkar (Bloomfield Hills, MI); Sergey T. Boldarev (Moscow, RU)
Assignee: Cryodynamics, LLC
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Quick Facts
Patent No.
US 8,591,503
App. No.
12/018,403
Granted
Nov 26, 2013
Kind
B2
Abstract

A gas-based cryotherapy probe is provided with a shaft having a closed distal end adapted for insertion into a body. A supply conduit is disposed longitudinally within the shaft for flowing gas towards the distal end, and a return conduit is disposed longitudinally within the shaft for flowing gas from the distal end. The gas is maintained at a lower pressure within the return conduit than in the supply conduit. A heat exchanger is disposed within the shaft in thermal communication with the supply conduit and return conduit to exchange heat from gas in the supply conduit to gas in the return conduit. A vacuum jacket is adapted to provide thermal isolation of the heat exchanger from the shaft.

Claims (15)

1. A cryotherapy system comprising:

a cryoengine for generating nitrogen under physical conditions near a critical point of a liquid-vapor system for the nitrogen, wherein the critical point defines a point in a phase diagram of the liquid-vapor system where molar volumes are substantially equivalent for liquid and gas, wherein the physical conditions comprise a pressure of about 33.5 atm; and

at least one crvotherapv probe comprising:

a shaft having a closed distal end adapted for insertion into a body;

an inlet capillary disposed within the shaft for providing a supply flow of cryogenic fluid;

an outlet capillary disposed within the shaft for providing a return flow of cryogenic fluid; and

a vacuum jacket adapted to provide thermal isolation of the inlet and outlet capillaries within the shaft from the shaft,

wherein the shaft, the inlet capillary, the outlet capillary, and the vacuum jacket are configured to circulate said nitrogen through the cryotherapy probe, and wherein vapor lock associated with cooling of the at least one cryotherapy probe is avoided.

2. The cryotherapy system recited in claim 1 wherein the shaft comprises a nonmagnetic body and a metallic tip at the distal end of the shaft.

3. The cryotherapy system recited in claim 1 wherein the shaft comprises a plurality of injection ports for injection of fluids.

4. The cryotherapy system recited in claim 1 further comprising electrical wiring disposed within the vacuum jacket.

5. The cryotherapy system recited in claim 4 wherein the electrical wiring comprises multifunction electrical wiring configured to permit multiple-point temperature monitoring of the distal end.

6. The cryotherapy system recited in claim 5 wherein the multifunction electrical wiring is configured to provide electrical stimulation of the body.

7. The cryotherapy system recited in claim 1 wherein the shaft has a diameter less than 2 mm.

8. The cryotherapy system recited in claim 1 wherein the shaft has a diameter less than 1 mm.

Assignments (5)
SECURITY INTEREST Recorded Jul 31, 2024
From: ADAGIO MEDICAL HOLDINGS, INC.
To: ALLEGRO MANAGEMENT LLC
Reel/Frame 068236/0236 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 10, 2014
From: CRYODYNAMICS, LLC
To: ADAGIO MEDICAL, INC.
Reel/Frame 032187/0117 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2008
From: LITTRUP, PETER J.; BABKIN, ALEXEI V.; DUNCAN, ROBERT V.; KERKAR, PRAMOD; BOLDAREV, SERGEY
To: MEDIPHYSICS LLP
Reel/Frame 020805/0117 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2008
From: MEDIPHYSICS LLP
To: CRYODYNAMICS, LLC
Reel/Frame 020805/0540 →
LICENSE Recorded Apr 15, 2008
From: CRYODYNAMICS, LLC
To: ENDOCARE, INC.
Reel/Frame 020805/0976 →
Continuity (3)
Continuation 10757768 · Jan 14, 2004
Provisional Application 60440541 · Jan 15, 2003
Related Publication 20080119836A1 · May 22, 2008