Method of producing a radially expandable prosthesis
View Patent ↗A method for producing a radially expandable prosthesis by cutting a pattern in a tubular member, which member has an outer diameter at least as great as the expanded diameter of the prosthesis.
1. A method of producing a radially expandable prosthesis, comprising:
providing a tubular member having an outer diameter;
cutting a pattern in the tubular member to provide a tubular prosthesis where the tubular prosthesis is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;
where the tubular member outer diameter is at least as great as the prosthesis expanded diameter.
2. The method of claim 1 , where the pattern comprises anchoring members.
3. The method of claim 2 , where the anchoring members comprise integral barbs.
4. The method of claim 1 , where the pattern comprises notches.
5. The method of claim 1 , further comprising forming at least one cavity in the prosthesis.
6. The method of claim 5 , where the at least one cavity is at least partially loaded with a therapeutic agent.
7. The method of claim 5 , where the at least one cavity is at least partially loaded with a radiopaque material.
8. The method of claim 1 , further comprising finishing the prosthesis.
9. The method of claim 8 , where the finishing comprises electro-polishing the prosthesis.
10. The method of claim 1 , further comprising coating the prosthesis with a therapeutic agent.
11. The method of claim 10 , where the therapeutic agent is selected from the group consisting of anti-inflammatory/immunomodulators, antiproliferatives, migration inhibitors/ECM-modulators, and agents that promote healing.
12. The method of claim 11 , where the therapeutic agent comprises paclitaxel or a paclitaxel derivative.
13. The method of claim 1 , where the tubular member comprises material selected from the group consisting of stainless steel, nitinol, tantalum, a nonmagnetic nickel-cobalt-chromium-molybdenum alloy, platinum, titanium, a suitable biocompatible alloy, a suitable biocompatible material, and a combination thereof.
14. The method of claim 13 , where the tubular member material comprises nitinol or stainless steel.
15. A method of producing a radially expandable prosthesis, comprising:
providing a tubular member having an outer diameter;
laser cutting a continuous pattern in the tubular member to provide a tubular prosthesis where the tubular prosthesis is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;
where the tubular member outer diameter is at least as great as the prosthesis expanded diameter.
16. The method of claim 15 , where the continuous pattern comprises a zigzag shape.
17. The method of claim 16 , where the zigzag shape comprises apexes and struts, the apexes comprising a smaller width than the struts.
18. The method of claim 16 , where the continuous pattern further comprises integral barbs.
19. The method of claim 16 , where the continuous pattern further comprises notches.
20. A method of producing a radially expandable stent, comprising:
providing a tubular member having an outer diameter;
laser cutting a zigzag pattern to provide a zigzag stent comprising apexes and struts;
where the zigzag stent is adapted to have a compressed diameter for endoluminal delivery and an expanded diameter for use upon implantation;
where the apexes have a width less than the struts;
where the struts comprise integral barbs;
where the tubular member outer diameter is at least as great as the expanded diameter of the stent.