IP Library Granted Patent US 7,602,183
Granted Patent B2
US 7,602,183 · App. 12/029,583 · Granted Oct 13, 2009

K-T sparse: high frame-rate dynamic magnetic resonance imaging exploiting spatio-temporal sparsity

Assignee: The Board of Trustees of the Leland Stanford Junior University
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Quick Facts
Patent No.
US 7,602,183
App. No.
12/029,583
Granted
Oct 13, 2009
Kind
B2
Abstract

A method of dynamic resonance imaging is provided. A magnetic resonance imaging excitation is applied. Data in 2 or 3 spatial frequency dimensions, and time is acquired, where an acquisition order in at least one spatial frequency dimension and the time dimension are in a pseudo-random order. The pseudo-random order and enforced sparsity constraints are used to reconstruct a time series of dynamic magnetic resonance images.

Claims (113)

1. A method of dynamic resonance imaging, comprising:

a) applying a magnetic resonance imaging excitation;

b) acquiring data in 2 or 3 spatial frequency dimensions, and time, where an acquisition order in at least one spatial frequency dimension and the time dimension are in a pseudo-random order, and

c) using the pseudo-random order and enforced sparsity constraints to reconstruct a time series of dynamic magnetic resonance images.

2. The method, as recited in claim 1 , wherein the using the pseudo-random order and enforced sparsity constraints to construct dynamic magnetic resonance images, comprises performing an optimization that enforces sparcity of the time-series images in a transform domain, which uses a sparcifying transform.

3. The method, as recited in claim 2 , wherein the number of pseudo-random acquisitions is less than half of the total number of acquisitions for a full data set that would completely define an image.

4. The method, as recited in claim 3 , wherein a defined number n of k space values would completely define an image, wherein no more than ⅓ n k-space acquisitions are collected.

5. The method, as recited in claim 4 , wherein the using the pseudo-random order and enforced sparsity constraints to reconstruct dynamic magnetic resonance images uses a solution for the following non-linear convex optimization:

minimize

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t

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1

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6. The method of claim 5 , wherein the sparcifying transform is an image compression transform.

7. The method, as recited in claim 6 , wherein the dynamic magnetic resonance images are created in real time.

8. The method, as recited in claim 6 , further comprising displaying the dynamic magnetic resonance images, wherein the dynamic magnetic resonance images are displayed in real time.

9. The method, as recited in claim 6 , wherein the sparcifying transform is a wavelet transform in the spatial dimension and a Fourier transform in a temporal direction.

10. The method of claim 2 , wherein the sparcifying transform from claim 2 is an image compression transform.

11. The method, as recited in claim 1 , wherein the using the pseudo-random order to reconstruct dynamic magnetic resonance images uses a solution for the following non-linear convex optimization:

minimize

Ψ

s

Ψ

t

m

1

s

.

t

.

F

u

m

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2

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12. The method, as recited in claim 1 , wherein the number of pseudo-random acquisitions is less than half of the total number of acquisitions for a full data set that would completely define an image.

13. The method, as recited in claim 1 , wherein a defined number n of k space values would completely define an image, wherein no more than ⅓ n k-space acquisitions are collected.

14. The method, as recited in claim 1 , further comprising displaying the series of dynamic magnetic resonance images.

15. A magnetic resonance imaging apparatus, comprising:

a magnetic resonance imaging excitation and detection system; and

a controller electrically connected to the magnetic resonance imaging excitation and detection system, comprising:

a display;

at least one processor; and

computer readable media, comprising:

computer readable code for applying a magnetic resonance imaging excitation;

computer readable code for acquiring data in 2 or 3 spatial frequency dimensions, and time, where an acquisition order in at least one spatial frequency dimension and the time dimension are in a pseudo-random order;

computer readable code for using the pseudo-random order and enforced sparsity constraints to reconstruct a time series of dynamic magnetic resonance images; and

computer readable code for displaying the time series of dynamic magnetic resonance images on the display.

16. The magnetic resonance imaging apparatus, as recited in claim 15 , wherein the computer readable code for using the pseudo-random order and enforced sparsity constraints to construct dynamic magnetic resonance images, comprises computer readable code for performing an optimization that enforces sparcity of the time-series images in a transform domain, which uses a sparcifying transform.

17. The magnetic resonance imaging apparatus, as recited in claim 16 , wherein the number of pseudo-random acquisitions is less than half of the total number of acquisitions for a full data set that would completely define an image and wherein a defined number n of k space values would completely define an image, wherein no more than ⅓ n k-space acquisitions are collected.

18. The magnetic resonance imaging apparatus, as recited in claim 17 , wherein the computer readable code for using the pseudo-random order and enforced sparsity constraints to reconstruct dynamic magnetic resonance images uses the solution for the following non-linear convex optimization:

minimize

Ψ

s

Ψ

t

m

1

s

.

t

.

F

u

m

-

y

2

<

ɛ

.

19. The magnetic resonance imaging apparatus of claim 18 , wherein the sparcifying transform is an image compression transform.

20. The magnetic resonance imaging apparatus, as recited in claim 16 , wherein the sparcifying transform is a wavelet transform in the spatial dimension and a Fourier transform in a temporal direction.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 27, 2008
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 020999/0460 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 8, 2008
From: LUSTIG, MICHAEL; SANTOS, JUAN M.; PAULY, JOHN M.; DONOHO, DAVID L.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 020922/0774 →
Continuity (2)
Provisional Application 6088964800 · Feb 13, 2007
Related Publication 20080197842A1 · Aug 21, 2008