Method and System for Tissue Fastening
Fastening devices are provided that are designed to effectively close tissue as well as instruments for applying the inventive fastening devices. The devices are useful for closing tissue such as mucosa in the oral cavity, oropharynx, hypopharynx, laryngeal surfaces, oronasopharynx, or other mucosal tissues. In particular, uvulopalatopharyngoplasty (UPPP), uvulopalatal flap (UPF) technique, and tonsillectomy can be assisted using the inventive system. Embodiments also provide methods of using the fastening devices and/or instruments, and kits including the fastening devices.
1 . A fastening device for fastening tissue, the fastening device comprising:
a body that forms a partial ring shape, wherein the body comprises:
an interior surface directed towards the center of the partial ring shape, wherein the interior surface is substantially flat; and
an exterior surface directed away from the center of the partial ring shape;
a first fastening member disposed on a first end of the body; and
a second fastening member disposed on a second end of the body.
2 . The fastening device of claim 1 , wherein the first fastening member and the second fastening member are each configured to pierce tissue.
3 . The fastening device of claim 2 , wherein the tissue is mucosal tissue.
4 . The fastening device of claim 1 , wherein the first fastening member and the second fastening member are configured to be coupled together.
5 . The fastening device of claim 1 , wherein the body comprises a hinge so that the first fastening member can be brought closer to the second fastening member.
6 . The fastening device of claim 1 , wherein the device is made of a biocompatible, bioresorbable material.
7 . The fastening device of claim 1 , wherein the device is coated with a protein or growth factor-based product to enhance healing of the tissue during use.
8 . The fastening device of claim 1 , wherein the first end of the body is configured to be fused to the second end of the body.
9 . A kit for fastening tissue, the kit comprising:
a plurality of fastening devices according to claim 1 , wherein the plurality of fastening devices comprise fastening devices of different sizes; and
a first instrument for fastening the fastening devices to tissues.
10 . The kit of claim 9 , further comprising:
pharmaceutical agents;
a second instrument for removing the fastening devices; and
instructions for using the fastening devices, the first instrument, and the second instrument.
11 . A method of fastening tissue, the method comprising:
providing a fastening device according to claim 1 ;
approximating a first portion of tissue to a second portion of tissue;
piercing the first portion of tissue with the first fastening member; and
piercing the second portion of tissue with the second fastening member, wherein the interior surface of the partial ring structure engages the first portion of tissue and the second portion of tissue.
12 . The method of claim 11 , further comprising:
crimping the body after piercing the first portion of tissue with the first fastening member and the second portion of tissue with the second fastening member.
13 . The method of claim 11 , wherein the fastening device is included in a cassette of multiple fastening devices.
14 . The method of claim 11 , further comprising:
utilizing an instrument to place the fastening device in a desired location; and
actuating the instrument to cause the first fastening member to pierce the first portion of the tissue.
15 . The method of claim 11 , wherein the steps are performed in the context of a uvulopalatopharyngoplasty (UPPP) with or without tonsillectomy procedure.
16 . The method of claim 11 , wherein the steps are performed in the context of a tonsillectomy procedure.
17 . The method of claim 11 , wherein the steps are performed in the context of a uvulopalatal flap (UPF) procedure.
18 . A method of fastening tissue, the method comprising:
providing a fastening device with a first fastening member configured to pierce tissue and a second fastening member configured to couple to the first fastening member;
locating the fastening device proximal to a first portion of tissue and a second portion of tissue;
piercing the first portion of tissue with the first fastening member;
piercing the second portion of tissue with the first fastening member; and
coupling the first fastening member to the second fastening member.
19 . The method of claim 18 , wherein the fastening device comprises a substantially flat surface that engages the first portion of tissue and the second portion of tissue.
20 . The method of claim 18 , wherein the fastening device is included in a cassette of multiple fastening devices.
21 . The method of claim 18 , further comprising:
utilizing an instrument to place the fastening device in a desired location; and
actuating the instrument to cause the first fastening member to pierce the first portion of the tissue.
22 . The method of claim 18 , wherein the first fastening member comprises a sharp point and the second fastening member comprises an aperture configured to receive the first fastening member.
23 . The method of claim 18 , wherein the steps are performed in the context of a uvulopalatopharyngoplasty (UPPP) with tonsillectomy procedure.
24 . The method of claim 18 , wherein the steps are performed in the context of a tonsillectomy procedure.
25 . The method of claim 18 , wherein the steps are performed in the context of a uvulopalatal flap (UPF) procedure.