IP Library Granted Patent US 8,163,008
Granted Patent B2
US 8,163,008 · App. 12/037,025 · Granted Apr 24, 2012

Leaflet valve

Assignee: Heart Leaflet Technologies, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,163,008
App. No.
12/037,025
Granted
Apr 24, 2012
Kind
B2
Abstract

A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention.

Claims (35)

1. A heart valve, transluminally deliverable via a catheter, comprising:

a mesh housing; and,

a flow control mechanism of biologic tissue coupled to said housing, said flow control mechanism including passive leaflets, free from biasing mechanisms;

said housing including an anchoring mechanism having at least one end free to extend radially to affix the heart valve to tissue of a leaflet of a native heart valve;

wherein said mesh housing is adapted to be compressed into the catheter for transluminal delivery, and to expand to a desired diameter upon deployment from said catheter.

2. A heart valve according to claim 1 , wherein said at least one end comprises an expandable cuff for engaging a leaflet of a native human heart valve.

3. A heart valve according to claim 2 , wherein said cuff includes a plurality of radial extensions extending from said cuff and engageable with said leaflet of a native heart valve so as to secure said cuff in said leaflet of a native heart valve.

4. A heart valve according to claim 1 , wherein said flow control mechanism comprises a sleeve containing a plurality of valve members.

5. A heart valve according to claim 4 , wherein said plurality of valve members includes leaflets disposed on a stent form.

6. The heart valve of claim 1 , wherein said mesh housing is comprised of Nitinol.

7. The heart valve of claim 1 , wherein said anchoring mechanism includes an upstream and downstream component for further fixating said housing.

8. The heart valve of claim 7 , wherein said upstream and downstream components fold outwardly when released.

9. A device, transluminally deliverable via a catheter, to increase fluid flow through a mammalian valve comprising:

a valve mechanism, of biologic tissue, containing a lumen therein;

said valve mechanism actuatable so as to place said lumen in one of an open and closed state;

said valve mechanism including leaflets that are passive, influenced to one of said open and closed states only by fluid flow; and,

a housing connected to said valve mechanism;

said housing including an anchoring structure with an end free to extend radially against tissue of a leaflet of said mammalian valve;

wherein said housing is constructed of mesh, allowing the housing to be compressed into a catheter for delivery and expands to a desired diameter upon deployment from said catheter.

10. The heart valve of claim 9 , wherein said housing is comprised of Nitinol.

11. The heart valve of claim 9 , wherein said anchoring structure includes an upstream and downstream component for further fixating said housing structure.

12. The heart valve of claim 11 , wherein said upstream and downstream components fold outwardly when released.

13. A valve device, transluminally deliverable via a catheter, for treating a diseased valve comprising:

a fluid flow control element comprised of biologic tissue, said fluid flow control element including passive leaflets, free from biasing mechanisms;

a housing structure constructed of a stiff fabric and having an outwardly radiating free end for anchoring said fluid flow control element adjacent to tissue of a native valve leaflet;

said fluid flow control element and said stiff fabric structure being connected to each other.

14. The heart valve of claim 13 , wherein said mesh housing structure is comprised of Nitinol.

15. A valve device according to claim 13 , wherein said housing structure includes a cuff.

16. A valve device according to claim 13 , wherein said housing structure is expandable and includes a constraining device for constraining the expansion of said stiff fabric structure.

17. A heart valve, transluminally deliverable via a catheter, comprising: a compressible and expandable housing with a free end extending radially from at least one of two opposite ends of said stiff fabric body; and a prosthetic valve comprised of biologic material attached to an inside surface of said housing, said prosthetic valve including passive leaflets, free from biasing mechanisms, said housing constructed of a stiff fabric.

18. A heart valve, transluminally deliverable via a catheter, comprising:

a housing structure;

a flow control mechanism coupled to said position securement structure, said flow control mechanism including passive leaflets, free from biasing mechanisms;

said mesh housing having a position securement structure including an end that is free to radiate outwardly to engage a surface of a leaflet of a native heart valve;

wherein said housing structure comprises a mesh tube, allowing said entire housing structure to be expandable and collapsible.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 17, 2023
From: HLT, INC
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 063981/0141 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 063845 FRAME: 0975. ASSIGNOR(S) HEREBY CONFIRMS THE CHANGE OF NAME. Recorded Jun 7, 2023
From: HEART LEAFLET TECHNOLOGIES, INC.
To: HLT, INC.
Reel/Frame 063888/0636 →
CHANGE OF NAME Recorded Jun 2, 2023
From: HEART LEAFLET TECHNOLOGIES, INC.
To: HTL, INC.
Reel/Frame 063845/0975 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 25, 2023
From: WILSON, ROBERT FOSTER; WILSON, SCOTT ROBERT; POKORNEY, JAMES L.
To: HEART LEAFLET TECHNOLOGIES, INC.
Reel/Frame 063766/0853 →
FIRST AMENDMENT TO SECURITY AGREEMENT Recorded Aug 25, 2009
From: HLT, INC.
To: BRACCO AMT, INC.
Reel/Frame 023134/0511 →
SECURITY AGREEMENT Recorded Mar 31, 2009
From: HLT INC.
To: BRACCO AMT, INC.
Reel/Frame 022473/0611 →
Continuity (3)
Continuation 10651162 · Aug 28, 2003
Provisional Application 60407414 · Aug 28, 2002
Related Publication 20080147105A1 · Jun 19, 2008