Granted Patent B2

US 8,606,761 · App. 12/049,330 · Granted Dec 10, 2013

Inventors: Andrew Alexander Kenedy (Sugar Land, TX); Charles Anthony Eldering (Furlong, PA)

Assignee: Expanse Bioinformatics, Inc.

Abstract

Claims (40)

1. A computer based method for determining a set of modifiable non-pangenetic attributes to allow an individual to achieve a desired lifestyle based on a set of pangenetic attributes associated with the individual comprising:

a) receiving, over a computer network, a query associated with the individual, wherein the query contains a specific desired lifestyle element;

b) accessing an attribute profile associated with the individual, the attribute profile containing pangenetic and non-pangenetic attributes;

c) accessing a database containing attribute combinations of pangenetic and non-pangenetic attributes of other individuals in a population that are statistically associated with the specific desired lifestyle element identified in (a), wherein the attribute combinations that are statistically associated with the specific desired lifestyle element contain pangenetic and non-pangenetic attributes of the other individuals in the population, and wherein the database further contains corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element;

d) determining, based on correlating the pangenetic attributes associated with the individual with the pangenetic attributes of the other individuals in the population that are statistically associated with the specific desired lifestyle element, a set of non-pangenetic attributes that are part of the attribute combinations that are statistically associated with the specific desired lifestyle element and which have corresponding pangenetic attributes correlated with the pangenetic attributes of the individual;

e) selecting the set of modifiable non-pangenetic attributes which, based on the corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element, will result in a statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual based on the correlation of their personal combination of pangenetic attributes in (d); and

f) transmitting the set of modifiable non-pangenetic attributes.

2. The method of claim 1 wherein the transmitted set of modifiable non-pangenetic attributes is a rank ordered list.

3. The method of claim 2 wherein the rank ordered list is ordered according to the modifiable non-pangenetic attributes having the highest statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual.

4. The method of claim 1 wherein the specific desired lifestyle element is longevity.

5. The method of claim 1 wherein the specific desired lifestyle element is weight control.

6. The method of claim 1 wherein the specific desired lifestyle element is disease avoidance.

7. A non-transitory program storage device readable by a machine and containing a set of instructions which, when read by the machine, causes execution of a computer based method for determining an approach to achieve a desired lifestyle for an individual, comprising:

a) receiving, over a computer network, a query associated with the individual, wherein the query contains a specific desired lifestyle element;

b) accessing an attribute profile associated with the individual, the attribute profile containing pangenetic and non-pangenetic attributes;

c) accessing a database containing attribute combinations of pangenetic and non-pangenetic attributes other individuals in a population that are statistically associated with the specific desired lifestyle element specified in (a), wherein the attribute combinations that are statistically associated with the specific desired lifestyle element contain pangenetic and non-pangenetic attributes of the other individuals in the population, and wherein the database further contains corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element;

d) determining, based on correlating the pangenetic attributes associated with the individual with the pangenetic attributes of the other individuals in the population that are statistically associated with the specific desired lifestyle element, a set of non-pangenetic attributes that are part of the attribute combinations that are statistically associated with the specific desired lifestyle element and which have corresponding pangenetic attributes correlated with the pangenetic attributes of the individual;

e) selecting the set of modifiable non-pangenetic attributes which, based on the corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element, will result in a statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual based on the correlation of their personal combination of pangenetic attributes in (d); and

f) transmitting the set of modifiable non-pangenetic attributes.

8. The program storage device of claim 7 wherein the transmitted set of modifiable non-pangenetic attributes is a rank ordered list.

9. The program storage device of claim 7 wherein the rank ordered list is ordered according to the non-modifiable attributes having the highest statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual.

10. The program storage device of claim 7 wherein the specific desired lifestyle element is longevity.

11. The program storage device of claim 7 wherein the specific desired lifestyle element is weight control.

12. The program storage device of claim 7 wherein the specific desired lifestyle element is disease avoidance.

13. A database system for determining a set of modifiable non-pangenetic attributes to allow an individual to achieve a desired lifestyle based on a set of pangenetic attributes associated with the individual comprising:

a) a memory containing:

i. a first data structure containing an attribute profile associated with the individual, the attribute profile comprising pangenetic and non-pangenetic attributes;

ii. a second data structure containing attribute combinations of other individuals in a population that are statistically associated with the specific desired lifestyle element, wherein the attribute combinations that are statistically associated with the specific desired lifestyle element contain pangenetic and non-pangenetic attributes of the other individuals in the population, and wherein the database further contains corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element;

b) a processor for:

i. receiving, over a computer network, a query associated with the individual, wherein the query contains a specific desired lifestyle element;

ii. accessing the attribute profile associated with the individual as stored in the first data structure, the attribute profile containing pangenetic and non-pangenetic attributes;

iii. accessing the second data structure containing attribute combinations of pangenetic and non-pangenetic attributes of other individuals in a population that are statistically associated with the specific desired lifestyle element, wherein the attribute combinations that are statistically associated with the specific desired lifestyle element contain pangenetic and non-pangenetic attributes of the other individuals in the population, and wherein the database further contains corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element;

iv. determining, based on correlating the pangenetic attributes associated with the individual with the pangenetic attributes of the other individuals in the population that are statistically associated with the specific desired lifestyle element, a set of non-pangenetic attributes that are part of the attribute combinations that are statistically associated with the specific desired lifestyle element and which have corresponding pangenetic attributes correlated with the pangenetic attributes of the individual;

v. selecting the set of non-pangenetic attributes that are modifiable by the individual and which, based on the corresponding statistical results which indicate the strength of association of the attribute combinations with the specific desired lifestyle element, will result in a statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual based on the correlation of their personal combination of pangenetic attributes in (iv); and

vi. transmitting the set of non-pangenetic attributes.

14. The database system of claim 13 wherein the transmitted set of non-pangenetic attributes is a rank ordered list.

15. The database system of claim 14 wherein the rank ordered list is ordered according to the non-modifiable attributes having the highest statistically significant increase in the probability of achieving the desired lifestyle if implemented by the individual.

16. The database system of claim 13 wherein the specific desired lifestyle element is longevity.

17. The database system of claim 13 wherein the specific desired lifestyle element is weight control.

18. The database system of claim 13 wherein the specific desired lifestyle element is disease avoidance.

Assignments (9)

Continuity (2)