IP Library Granted Patent US 7,754,250
Granted Patent B2
US 7,754,250 · App. 12/051,716 · Granted Jul 13, 2010

Composition and methods for treating Alzheimer's disease and other amyloidoses

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Quick Facts
Patent No.
US 7,754,250
App. No.
12/051,716
Granted
Jul 13, 2010
Kind
B2
Abstract

A method of treating an amyloid disease in a patient or inhibiting the formation, deposition, accumulation, or persistence, of amyloid fibrils, amylin fibrils, or islet amyloid fibrils, and/or dissolving or disrupting pre-formed or pre-deposited amyloid fibrils in type II diabetes in a mammalian subject. In the method a therapeutically effective amount of plant matter form the genus Uncaria , species Tomentosa is administered, preferably from the inner bark or root tissue of Uncaria Tomentosa.

Claims (9)

1. A method of treating an amyloid disease in a patient, comprising administering to the patient an amount of plant matter from Uncaria tomentosa.

2. The method claim 1 wherein the plant matter is administered orally.

3. The method claim 1 wherein the plant matter is administered by aerosol spray.

4. The method claim 1 wherein the plant matter is administered in a parenterally injectable or infusible form.

5. The method of claim 1 wherein the amyloid disease is type II diabetes.

6. A method for reducing, disrupting, dissolving or inhibiting islet amyloid and amylin fibrils in a patient comprising administration of plant matter from Uncaria tomentosa.

7. The method claim 6 wherein the plant matter is administered orally.

8. The method claim 6 wherein the plant matter is administered by aerosol spray.

9. The method claim 6 wherein the plant matter is administered in a parenterally injectable or infusible form.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2009
From: PROTEOTECH INC
To: UNIVERSITY OF WASHINGTON
Reel/Frame 023214/0328 →