Disinfectant with quarternary ammonium polymer and copolymers
An alcohol-soluble, water-insoluble, disinfectant composition and a method of using the same for disinfecting and for providing a prolonged antimicrobial property to a variety of surfaces, including skin. The composition comprises an antimicrobial polymer that is capable of imparting an antimicrobial property to a surface without the use of a metal or metal-containing compound. The composition is applied to a surface and allowed to evaporate leaving a coating of antimicrobial polymer.
1. An antimicrobial composition comprising a polyurethane polymer dissolved in a solvent consisting essentially of alcohol, the polyurethane polymer being readily soluble in the solvent but insoluble in water,
wherein the polyurethane polymer comprises monomeric moieties containing at least one quaternary ammonium group,
wherein said monomeric moieties provide at least 10% of the total weight of said polyurethane polymer and are incorporated into the molecular structure of the polyurethane polymer by covalent chemical bonding via either polymerization with other monomers or reaction with an existing polymer, and
wherein said quaternary ammonium group is in the main-chain of the polyurethane polymer,
whereby said composition provides durable antimicrobial activity when applied to a surface.
2. The composition of claim 1 , wherein said monomeric moieties provide at least 25% of the total weight of said polyurethane polymer.
3. The composition of claim 1 , wherein a dye is incorporated into the molecular structure of the polyurethane polymer by covalent chemical bonding via either polymerization with other monomers or reaction with an existing polyurethane polymer, thereby preventing migration of the dye from the polymer.
4. The composition of claim 3 , wherein the dye is fluorescein.
5. The composition of claim 1 , wherein said monomeric moieties are selected from the group of polyoxyethylenemonoalkylmethylammonium salts.
6. The composition of claim 1 , wherein said antimicrobial polymer is synthesized using step-growth polymerization.
7. The composition of claim 1 , wherein said solvent consists essentially of one or more alcohols selected from the group consisting of ethanol, methanol, and isopropanol.
8. The composition of claim 1 , wherein said solvent is comprised of 60-95% by weight of said alcohol.
9. The composition of claim 1 , wherein said polyurethane polymer has an antimicrobial activity which does not require leaching, elution, or releasing from the surface to which the antimicrobial composition is applied.
10. The composition of claim 1 , wherein said composition has a pH between 5 and 9.
11. The composition of claim 1 , wherein said composition is in a form selected from the group consisting of liquid, gel, foam, and aerosol.
12. The composition of claim 1 , wherein said antimicrobial composition further comprises at least one additive selected from the group consisting of a drug, an antimicrobial agent, an antiseptic agent, a thickening agent, a moisturizer, an emollient, a vitamin, a temporary dye, a permanent dye, and a UV absorber.
13. The composition of claim 12 , wherein said additive is an emollient.
14. The composition of claim 13 , wherein said emollient is propylene glycol, dipropylene glycol, glycerol, or a mixture thereof.