IP Library Granted Patent US 7,846,902
Granted Patent B2
US 7,846,902 · App. 12/066,849 · Granted Dec 7, 2010

Dipeptide-comprising composition for oral administration

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Quick Facts
Patent No.
US 7,846,902
App. No.
12/066,849
Granted
Dec 7, 2010
Kind
B2
Abstract

A composition for oral administration is provided, which includes at least one dipeptide represented by the formula: (wherein X represents alanyl, and Y represents valine, leucine or isoleucine), with an object of providing a composition for oral administration which is excellent in nutrition, pharmacological effect and gustation, or providing a composition for oral administration which is excellent in processing characteristics such as solubility and tableting property.

Claims (20)

1. A method comprising the step of orally administering to a human a composition, said composition comprising a comestible carrier and at least one dipeptide, wherein all dipeptides in said composition are represented by the formula:

wherein X is alanyl, and Y is selected from the group consisting of valine, leucine and isoleucine.

2. The method according to claim 1 , wherein the composition is a nutritious food or a drug product.

3. The method according to claim 2 , wherein the composition is a beverage.

4. The method according to claim 2 , wherein the composition is a drug product comprising a pharmaceutically acceptable carrier.

5. The method according to claim 4 , wherein the composition is a tablet or a granule.

6. The method according to claim 1 , wherein the composition comprises three dipeptides wherein Y is each of valine, leucine and isoleucine, respectively.

7. The method according to claim 6 , wherein the composition further comprises at least one kind of amino acid selected from the group consisting of valine, leucine and isoleucine.

8. The method according to claim 1 , wherein the composition further comprises at least one amino acid selected from the group consisting of valine, leucine and isoleucine.

9. The method according to claim 6 , wherein the total content of leucine in the composition is 1 to 3 times the total content of valine or total content of isoleucine.

10. The method according to claim 7 , wherein the total content of leucine in the composition is 1 to 3 times the total content of valine or total content of isoleucine.

11. The method according to claim 8 , wherein the total content of leucine in the composition is 1 to 3 times the total content of valine or total content of isoleucine.

12. The method according to claim 1 , wherein Y is leucine, and the composition is a beverage.

13. The method according to claim 12 , wherein the composition further comprises isoleucine.

14. The method according to claim 1 , wherein the composition provides 0.1 to 20 g/day of the total amount of valine, leucine and isoleucine to said human.

15. The method according to claim 14 , wherein the composition provides 1 to 10 g/day of the total amount of valine, leucine and isoleucine to said human.

16. The method according to claim 15 , wherein the composition provides 2 to 7 g/day of the total amount of valine, leucine and isoleucine to said human.

17. The method according to claim 6 , wherein the composition provides 0.1 to 20 g/day of the total amount of valine, leucine and isoleucine to said human.

18. The method according to claim 17 wherein the composition provides 1 to 10 g/day of the total amount of valine, leucine and isoleucine to said human.

19. The method according to claim 18 , wherein the composition provides 2 to 7 g/day of the total amount of valine, leucine and isoleucine to said human.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2009
From: KYOWA HAKKO KOGYO CO., LTD.
To: KYOWA HAKKO BIO CO., LTD.
Reel/Frame 022578/0259 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2008
From: SAKAI, YASUSHI; KIMURA, MASAO; KAYAHASHI, SHUN; KAMIYA, TOSHIKAZU; HASHIMOTO, SHIN-ICHI; KAWABE, HIDEO
To: KYOWA HAKKO KOGYO CO., LTD.
Reel/Frame 021240/0252 →