Granted Patent
B2
US 7,569,597 · App. 12/070,322 · Granted Aug 4, 2009
Isoindoline compounds and methods of their use
Assignee:
Celgene Corporation
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Abstract
Novel isoindoline compounds are disclosed. Methods of treating, preventing and/or managing cancer, diseases and disorders associated with, or characterized by, undesired angiogenesis, and diseases and disorders mediated by PDE 4, using the compounds are also disclosed.
Claims (2)
1. A method of treating a disease or disorder mediated by PDE 4, which comprises administering to a patient in need of such treatment a therapeutically effective amount of a compound of the formula:
or a pharmaceutically acceptable salt, prodrug, or stereoisomer thereof, wherein the disease or disorder mediated by PDE 4 is asthma, chronic obstructive pulmonary disease, atopic dermatitis, rheumatoid arthritis, multiple sclerosis, or Crohn's disease.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 4, 2019
From: CELGENE CORPORATION
To: AMGEN INC.
Reel/Frame 051181/0038 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 15, 2008
From: MULLER, GEORGE W.; MAN, HON WAH
To: CELGENE CORPORATION
Reel/Frame 020583/0996 →
Continuity (2)