IP Library Granted Patent US 7,550,091
Granted Patent B2
US 7,550,091 · App. 12/070,487 · Granted Jun 23, 2009

Implant surface preparation

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Quick Facts
Patent No.
US 7,550,091
App. No.
12/070,487
Granted
Jun 23, 2009
Kind
B2
Abstract

The surface of a device that is surgically implantable in living bone is prepared. The device is made of titanium with a native oxide layer on the surface. The method of preparation comprises the steps of removing the native oxide layer from the surface of the device and performing further treatment of the surface substantially in the absence of unreacted oxygen.

Claims (44)

1. A method of preparing the surface of an implant to be surgically implanted in living bone and made of titanium, the implant having a surface with a native oxide layer thereon, the method comprising the steps of:

removing the native oxide layer from the surface;

acid etching the surface from which the native oxide layer has been removed to form a surface roughness; and

depositing a layer of hydroxyapatite on the acid-etched surface.

2. The method of claim 1 wherein the depositing occurs in the absence of oxygen.

3. The method of claim 1 wherein the depositing includes adhering, the adhering being enhanced by the roughness of the acid-etched surface.

4. The method of claim 1 wherein the depositing includes applying hydroxyapatite in the form of particles.

5. The method of claim 1 wherein the depositing includes applying hydroxapatite in the form of a film.

6. The method of claim 1 wherein the depositing includes applying hydroxyapatite so as not to disturb the surface from which the native oxide layer has been removed to form a surface roughness.

7. The method of claim 1 wherein the depositing includes applying hydroxyapatite using an inert atmosphere.

8. The method of claim 1 wherein the depositing includes distributing hydroxyapatite, the distributing being enhanced by the surface roughness.

9. The method of claim 1 wherein the removing the native oxide layer is carried out by an acid etching process.

10. The method of claim 1 wherein the surface roughness have peak-to-valley heights less than 10 microns.

11. The method of claim 1 wherein the acid-etching includes producing a surface roughness with an array of irregularities.

12. The method of claim 11 wherein the depositing includes applying hydroxyapatite in the form of fine particles that become entrapped on the irregularities.

13. The method of claim 11 wherein the depositing includes applying hydroxyapatite in the form of particles that become entrapped between the irregularities.

14. The method of claim 11 wherein the irregularities have peak-to-valley heights less than 10 microns.

15. A method of preparing a surface of a device that is surgically implantable in living bone, the device being made of titanium and having a native oxide layer on the surface, the method comprising the steps of:

removing the native oxide layer from the surface of the device until the depth of the peak-to-peak oxygen profile as measured by Auger spectrometer has decreased to one-half of the initial profile;

after the removing, performing a roughening treatment on the surface resulting from the removing to produce a roughened surface with an array of irregularities; and

after the performing a roughening treatment on the surface, depositing a layer of hydroxyapatite on the surface.

16. The method of claim 15 wherein the performing of the roughening treatment includes acid etching.

17. The method of claim 15 wherein the depositing occurs in the absence of oxygen.

18. The method of claim 15 wherein the depositing includes applying hydroxyapatite in the form of particles.

19. The method of claim 15 wherein the depositing includes applying hydroxapatite in the form of a film.

20. The method of claim 15 wherein the removing the native oxide layer is carried out by an acid etching process.

21. The method of claim 15 wherein the irregularities have peak-to-valley heights less than 10 microns.

22. The method of claim 15 wherein the depositing includes applying hydroxyapatite in the form of particles that become entrapped on the irregularities.

23. The method of claim 15 wherein the depositing includes applying hydroxyapatite in the form of particles that become entrapped between the irregularities.

24. The method of claim 15 wherein the depositing includes applying hydroxyapatite in the form of particles that become entrapped on and between the irregularities.

25. A method of preparing the surface of an implant to be surgically implanted in living bone and made of titanium, the implant having a surface with a native oxide layer thereon, the method comprising the steps of:

removing the native oxide layer from the surface;

acid etching the surface from which the native oxide layer has been removed to form a surface roughness; and

depositing a layer of bone growth enhancing material on the acid-etched surface.

26. The method of claim 25 wherein the depositing includes applying the bone growth enhancing material in the form of particles.

27. The method of claim 25 wherein the depositing includes applying the bone growth enhancing material in the form of a film.

28. The method of claim 25 wherein the bone growth enhancing material is hydroxyapatite.

29. The method of claim 25 wherein the removing the native oxide layer is carried out by an acid etching process.

30. The method of claim 25 wherein the surface roughness includes irregularities having peak-to-valley heights less than 10 microns.

31. The method of claim 25 wherein the acid-etching includes producing a surface roughness with an array of irregularities.

32. The method of claim 1 , further including the act of grit blasting the surface prior to the act of removing the native oxide layer.

33. The method of claim 32 , wherein the act of grit blasting includes using titanium grit.

34. The method of claim 15 , further including the act of grit blasting the surface prior to the act of removing the native oxide layer.

35. The method of claim 34 , wherein the act of grit blasting includes using titanium grit.

Assignments (6)
RELEASE OF SECURITY INTEREST IN PATENTS RECORDED AT REEL 023505/ FRAME 0241 Recorded Nov 23, 2015
From: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
To: LVB ACQUISITION, INC.; BIOMET, INC.; BIOMET 3I, LLC; BIOMET BIOLOGICS, LLC.; BIOMET EUROPE LTD.; BIOMET FAIR LAWN LLC; BIOMET HOLDINGS LTD.; BIOMET INTERNATIONAL LTD.; BIOMET LEASING, INC.; BIOMET MANUFACTURING CORPORATION; BIOMET MICROFIXATION, LLC; BIOMET ORTHOPEDICS, LLC; BIOMET SPORTS MEDICINE, LLC; BIOMET TRAVEL, INC.; BIOLECTRON, INC.; CROSS MEDICAL PRODUCTS, LLC; ELECTR-OBIOLOGY, LLC; EBI HOLDINGS, LLC; EBI, LLC; EBI MEDICAL SYSTEMS, LLC; BIOMET FLORIDA SERVICES, LLC; INTERPORE CROSS INTERNATIONAL, LLC; INTERPORE SPINE, LTD.; KIRSCHNER MEDICAL CORPORATION; IMPLANT INNOVATIONS HOLDINGS, LLC
Reel/Frame 037155/0082 →
SECURITY AGREEMENT Recorded Nov 12, 2009
From: LVB ACQUISITION, INC.; BIOMET, INC.; BIOMET 3I, LLC; BIOMET BIOLOGICS, LLC; BIOMET EUROPE LTD.; BIOMET FAIR LAWN LLC; BIOMET HOLDINGS LTD.; BIOMET INTERNATIONAL LTD.; BIOMET LEASING, INC.; BIOMET MANUFACTURING CORPORATION; BIOMET MICROFIXATION, LLC; BIOMET ORTHOPEDICS, LLC; BIOMET SPORTS MEDICINE, LLC; BIOMET TRAVEL, INC.; BIOLECTRON, INC.; CROSS MEDICAL PRODUCTS, LLC; ELECTRO-BIOLOGY, LLC; EBI HOLDINGS, LLC; EBI, LLC; EBI MEDICAL SYSTEMS, LLC; BIOMET FLORIDA SERVICES, LLC; INTERPORE CROSS INTERNATIONAL, LLC; INTERPORE SPINE, LTD.; KIRSCHNER MEDICAL CORPORATION; IMPLANT INNOVATIONS HOLDINGS, LLC
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT FOR THE SECURED PARTIES
Reel/Frame 023505/0241 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE NAME AND ADDRESS: BIOMET 3I, INC. 4555 RIVERSIDE DRIVE, PALM BEACH GARDENS, FLORDIA 33410-4200 PREVIOUSLY RECORDED ON REEL 021279 FRAME 0298. ASSIGNOR(S) HEREBY CONFIRMS THE IMPLANT INNOVATIONS, INC. 3071 CONTINENTAL DRIVE, WEST PALM BEACH, FLORIDA 33407. Recorded May 12, 2009
From: BEATY, KEITH D.
To: IMPLANT INNOVATIONS, INC.
Reel/Frame 022673/0705 →
CHANGE OF NAME Recorded May 5, 2009
From: IMPLANT INNOVATIONS, INC.
To: BIOMET 3I, INC.
Reel/Frame 022637/0996 →
CHANGE OF NAME Recorded Aug 8, 2008
From: BIOMET 3I, INC.
To: BIOMET 3I, LLC
Reel/Frame 021354/0492 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 23, 2008
From: BEATY, KEITH D.
To: BIOMET 3I, INC.
Reel/Frame 021279/0298 →