Antineoplastic peptides
View Patent ↗The present invention provides antineoplastic peptides of formula I, R 1 R 2 N—CHX—CO—A—B-D-E-(G) s -K wherein R 1 , R 2 , X, A, B, D, E, G, K and s have the meanings stated in the description. The compounds have antineoplastic activity.
1. A pharmaceutical composition comprising a compound of the formula I:
Me 2 Val-Val-MeVal-Pro-Pro-NHC(CH 3 ) 3 (SEQ ID NO: 1) (I)
or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
2. The pharmaceutical composition of claim 1 , wherein the pharmaceutically acceptable salt is a hydrochloride salt.
3. A synthesized peptide of the formula I:
Me 2 Val-Val-MeVal-Pro-Pro-NHC(CH 3 ) 3 (SEQ ID NO: 1) (I).
4. A pharmaceutically acceptable salt of a synthesized peptide of the formula I:
Me 2 Val-Val-MeVal-Pro-Pro-NHC(CH 3 ) 3 (SEQ ID NO: 1) (I)
wherein the pharmaceutically acceptable salt is a hydrochloride salt.