IP Library Granted Patent US 8,673,368
Granted Patent B2
US 8,673,368 · App. 12/087,847 · Granted Mar 18, 2014

Cannabinoid-containing plant extracts as neuroprotective agents

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Quick Facts
Patent No.
US 8,673,368
App. No.
12/087,847
Granted
Mar 18, 2014
Kind
B2
Abstract

The invention relates to the use of cannabinoid-containing plant extracts in the prevention or treatment of neural degeneration. In particular, the invention relates to use of one or more cannabinoid-containing plant extracts in the prevention or treatment of neural degeneration, wherein the one or more cannabinoid-containing plant extracts comprise: i) a cannabinoid-containing fraction; and ii) a non-cannabinoid containing fraction.

Claims (7)

1. A method of treating a patient suffering from a condition selected from the group consisting of Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, frontotemporal dementia, prion disease, Lewy body dementia, progressive supranuclear palsy, vascular dementia, normal pressure hydrocephalus, traumatic spinal cord injury, HIV dementia, alcohol induced neurotoxicity, Down's syndrome and epilepsy consisting essentially of administering to said patient a therapeutically effective amount of a pharmaceutical formulation consisting essentially of an extract of Cannabis sativa , and wherein the extract of Cannabis sativa is obtained by supercritical or subcritical extraction with CO2, and is either

(a) a Cannabis sativa L. plant extract where a major cannabinoid is tetrahydrocannabinol (THC), and the extract consists essentially of

i) from 67.3-87.7% (w/w) of cannabinoid-containing components consisting essentially of the major cannabinoid; a minor cannabinoid; and one or more other cannabinoids; and

ii) from 12.3-32.7% (w/w) of non-cannabinoid components consisting essentially of terpenes; sterols; triglycerides; alkanes; squalene; tocopherol; carotenoids; chlorophyll; flavonoid; glycosides and alkaloids, or

(b) a Cannabis sativa L. plant extract where a major cannabinoid is cannabidiol (CBD) and the extract consists essentially of

i) from 65.8-95.5% (w/w) of cannabinoid-containing components consisting essentially of the major cannabinoid; a minor cannabinoid; and one or more other cannabinoids; and

ii) from 7.5-34.2% (w/w) of non-cannabinoid components consisting essentially of terpenes; sterols; triglycerides; alkanes; squalene; tocopherol; carotenoids; chlorophyll; flavonoid; glycosides and alkaloids.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded Oct 31, 2025
From: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
To: JAZZ PHARMACEUTICALS OPERATIONS UK LIMITED (F/K/A GW PHARMA LIMITED); JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (F/K/A GW RESEARCH LIMITED)
Reel/Frame 072747/0876 →
CHANGE OF NAME Recorded May 13, 2025
From: GW RESEARCH LIMITED
To: JAZZ PHARMACEUTICALS RESEARCH UK LIMITED
Reel/Frame 071097/0142 →
SECURITY AGREEMENT Recorded Jul 22, 2021
From: GW PHARMA LIMITED; GW RESEARCH LIMITED
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 056958/0493 →
DEED OF ASSIGNMENT OF INTELLECTUAL PROPERTY RIGHTS Recorded Feb 4, 2021
From: GW PHARMA LIMITED
To: GW RESEARCH LIMITED
Reel/Frame 055222/0457 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2009
From: GUY, GEOFFREY; PLATT, BETTINA
To: GW PHARMA LIMITED
Reel/Frame 022831/0914 →