Synergistic mixtures of bisabolol and ginger extract
View Patent ↗Described is a formulation having a skin irritation-reducing action consisting of or comprising: bisabolol and a composition or compound chosen from the group consisting of a) substance mixtures obtainable from an extraction of ginger, b) substance mixtures obtainable from a separation of a ginger extract which comprise a compound which is chosen from the group consisting of gingerols, shogaols, gingerdiols, dehydrogingerdiones, paradols and derivatives thereof and c) compounds obtainable from a separation of a ginger extract which are chosen from the group consisting of gingerols, shogaols, gingerdiols, dehydrogingerdiones, paradols and derivatives thereof and mixtures thereof, wherein the particular content of bisabolol and of the said composition or compound in the formulation is adjusted such that the skin irritation-reducing action of these contents is increased synergistically.
1. A skin irritation-reducing cosmetic formulation having skin-irritation reducing action comprising:
i) bisabolol; and
ii) (a) a ginger extract containing a compound selected from the group consisting of: gingerols, gingerdiols, shogaols, gingerdios, dehydrogingerdiones or paradols; or
(b) a compound obtained from a separation of a ginger extract, wherein the compound is selected chosen from the group consisting of: gingerols, shogaols, gingerdiols, dehydrogingerdiones, paradols or a mixture thereof;
wherein the weight ratio of component i) to component ii) is 100,000:1 to 10:1 and the skin irritation-reducing action of the combination of components i) and ii) is increased synergistically relative to the skin irritation-reducing action of components i) and ii) individually.
2. The cosmetic formulation of claim 1 , wherein components i) and ii) each individually have skin irritation-reducing action.
3. The cosmetic formulation of claim 1 , wherein component ii) is a ginger extract.
4. The cosmetic formulation of claim 1 , wherein the sum of components i) and ii) is at least 90 wt %, based upon the total weight of the formulation or component i) is present in an amount of 90-99.999 wt %, based upon the total weight of the formulation or component ii) is present in an amount of 0.001-10 wt %, based upon the total weight of the formulation.
5. A medicament for treating skin irritation, comprising the cosmetic formulation of claim 1 .
6. A kit comprising the cosmetic formulation of claim 1 .
7. The cosmetic formulation of claim 1 , wherein the formulation is a liquid formulation.
8. The liquid formulation of claim 7 comprising oil as a solvent.
9. The cosmetic formulation of claim 1 , wherein the formulation is a solid formulation.
10. The cosmetic formulation of claim 1 , wherein the weight ratio of component i) to component ii) is 1,000:1 to 50:1.
11. The cosmetic formulation of claim 4 , wherein the sum of components i) and ii) is at least 90 wt %, based upon the total weight of the formulation.
12. The cosmetic formulation of claim 4 , wherein component i) is present in an amount of 90-99.999 wt %, based upon the total weight of the formulation.
13. The cosmetic formulation of claim 4 , wherein component ii) is present in an amount of 0.001-10 wt %, based upon the total weight of the formulation.