Compounds for the treatment of metabolic disorders
View Patent ↗Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyper-lipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed as Formula (I).
1. A biologically active agent, wherein the agent is a compound of the formula:
wherein
n is 1;
one of m and x is 0 and the other is 0, 2, or 4;
q is 0;
t is 0;
R 3 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms;
one of R 4 and R 5 is alkyl having 1 carbon atom and the other is hydrogen;
A is 2,6-dimethylphenyl; and
R 1 is hydrogen or alkyl having 1 or 2 carbon atoms;
or when R 1 is hydrogen, a pharmaceutically acceptable salt of the compound.
2. The biologically active agent of claim 1 , wherein R 3 is hydrogen.
3. The biologically active agent of claim 2 , wherein the compound is 2-(3-(2,6-Dimethylbenzyloxy)-phenyl)-2-methylacetic acid.