IP Library Granted Patent US 10,251,899
Granted Patent B2
US 10,251,899 · App. 12/102,077 · Granted Apr 9, 2019

Method for improving stool characteristics in infants

Inventors: Nagendra Rangavajla (Newburgh, IN); Joaquin Franco (Newburgh, IN)
Assignee: MEAD JOHNSON NUTRITION COMPANY
A61K31/702A61K31/7016A61K35/745A61K35/747
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Quick Facts
Patent No.
US 10,251,899
App. No.
12/102,077
Granted
Apr 9, 2019
Kind
B2
Abstract

In accordance with the present invention, a novel method for improving the stool characteristics, reducing the incidence of diarrhea, and firming the stool of a formula-fed infant has been discovered. The method comprises administering to the infant at least one prebiotic and hydrolyzed pectin.

Claims (15)

1. A method for providing prebiotics to a formula-fed infant while producing firm stool in the infant, the method comprising administering to the infant a nutritional composition comprising a prebiotic mixture comprising polydextrose and galactooligosaccharide, between about 0.1 g and about 5 g per 100 kcal extensively hydrolyzed pectin having a peak molecular weight of 3,300 or less, and at least one insoluble fiber.

2. A method for providing prebiotics to a formula-fed infant while reducing the incidence of diarrhea in the infant, the method comprising administering to the infant a nutritional composition comprising a prebiotic mixture comprising polydextrose and galactooligosaccharide, between about 0.1 g and about 5 g per 100 kcal extensively hydrolyzed pectin having a peak molecular weight of 3,300 or less, and at least one insoluble fiber.

3. The method according to claim 2 wherein the amount of the prebiotic mixture is between about 1.0 g/L and 10.0 g/L of the nutritional composition.

4. The method according to claim 2 wherein the amount of the prebiotic mixture is between about 2.0 g/L and 8.0 g/L of the nutritional composition.

5. The method according to claim 2 wherein the amount of hydrolyzed pectin is between about 0.25 g and about 1 g per 100 kcal of the nutritional composition.

6. The method according to claim 1 wherein the amount of the prebiotic mixture is between about 1.0 and about 10.0 grams per liter of the nutritional composition.

7. The method according to claim 1 wherein the amount of the prebiotic mixture is between about 2.0 and about 8.0 grams per liter of the nutritional composition.

8. The method according to claim 1 wherein the amount of hydrolyzed pectin is between about 0.25 g and about 1 g per 100 kcal of the nutritional composition.

9. The method according to claim 1 , wherein the nutritional composition additionally comprises at least one long chain polyunsaturated fatty acid.

10. The method according to claim 9 , wherein the long chain polyunsaturated fatty acid comprises docosahexaenoic acid (DHA) or arachidonic acid (ARA).

11. The method according to claim 1 , wherein the nutritional composition additionally comprises at least one probiotic.

12. The method according to claim 11 , wherein the probiotic is selected from the group consisting of Bifidobacteria spp. and Lactobacillus spp.

13. The method according to claim 1 , wherein the at least one insoluble fiber is selected from the group consisting of oat hull fiber, soy fiber, pea fiber, beet fiber, cellulose and corn fiber, and a mixture thereof.

14. The method according to claim 2 , wherein the at least one insoluble fiber is selected from the group consisting of oat hull fiber, soy fiber, pea fiber, beet fiber, cellulose and corn fiber, and a mixture thereof.

15. The method according to claim 10 , wherein the nutritional composition comprises DHA and ARA, further wherein the weight ratio of ARA to DHA is from about 1:3 to 9:1.

Assignments (3)
MERGER Recorded Mar 9, 2009
From: MJN RESTRUCTURING HOLDCO, INC.
To: MEAD JOHNSON NUTRITION COMPANY
Reel/Frame 022354/0768 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 13, 2009
From: BRISTOL-MYERS SQUIBB COMPANY
To: MJN RESTRUCTURING HOLDCO, INC.
Reel/Frame 022248/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 14, 2008
From: RANGAVAJLA, NAGENDRA; FRANCO, JOAQUIN
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 020796/0140 →
Continuity (2)
Provisional Application 60978172 · Oct 8, 2007
Related Publication 20090092590A1 · Apr 9, 2009