IP Library Granted Patent US 8,316,849
Granted Patent B2
US 8,316,849 · App. 12/103,074 · Granted Nov 27, 2012

Integrated ventilator with calibration

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Quick Facts
Patent No.
US 8,316,849
App. No.
12/103,074
Granted
Nov 27, 2012
Kind
B2
Abstract

An integrated respiratory ventilation system and method for its calibration is described. The system includes a ventilator having air conduits, transducers adapted to emit signals proportional to the level of air pressure or air flow within the air conduits, and inspiration, expiration and exhaust ports. A processor-controlled calibrator is in communication with one or more of the air conduits. A preferred calibrator includes a water-filled outer column and a vertically aligned inner column extending into the outer column, the inner column having an upper end in communication with at least one of the ports. A processor controls the opening and closing of the ports and the level of air pressure in, and air flow from, the inner column to measure the level of transducer signals at two known pressures and two known flows. The processor uses the measured transducer signals to calibrate the transducer.

Claims (29)

1. A respiratory ventilator system comprising:

a) ventilator including inspiration and expiration ports, a pressurized air source, a pressure transducer for measuring it pressure, a flow transducer for measuring air flow, a flow control valve for regulating air flow, and a pressure regulator for regulating air pressure;

b) a processor for receiving air pressure and flow information from said transducers and controlling said flow control valve and air pressure in accordance with programmed instructions; and

c) a calibrator attachable to said inspiration port to calibrate said pressure and flow transducers, said calibrator measuring pressure transducer signals at two known pressure levels and flow transducer signals at two known flows and transmitting the measurements to said processor.

2. The ventilator system of claim 1 , wherein said calibrator is comprised of a water-filled outer column, in inner column extending into said outer column, and tubing connecting the upper end of said inner column to said inspiration port.

3. The ventilator system of claim 2 , wherein the first flow signal is zero, and the second flow signal is determined based on the volume of the inner tube and the time required to empty water from the inner tube.

4. The ventilator system of claim 2 , wherein the first pressure signal is zero and the second pressure signal is determined by the pressure required to fill the inner tube with water.

5. The ventilator system of claim 1 , further including a preamplifier, said signals being sent to said processor through said preamplifier.

6. The ventilator system of claim 1 , wherein one of said pressure transducer signals and one of said flow signals are zero.

7. The ventilator system of claim 1 , wherein said ventilator includes an exhaust port, and said flow transducer measures air flow from said exhaust port.

8. The ventilator of claim 1 , wherein said ventilator includes an air pressure reservoir with a bleed port controlled by said processor to regulate air pressure in said ventilator.

9. The ventilator system of claim 1 , wherein said processor assumes a straight line relationship between pressure levels and pressure signals, and between flow levels and flow signals.

10. The ventilator system of claim 1 , including pressure transducers to measure lung pressure, mouth pressure and reservoir pressure, said processor calibrating each of said transducers based on information received from said calibrator.

11. A respiratory ventilator system comprising:

a) a ventilator including inspiration and expiration ports, a pressurized air source, a pressure transducer for measuring air pressure, a flow transducer for measuring air flow, a flow control valve for regulating air flow, and a pressure regular for regulating air pressure;

b) a processor for receiving air pressure and flow information from said transducers and controlling said flow control valve and air pressure in accordance with programmed instructions; and

c) a calibrator attachable to said inspiration port to calibrate said pressure and flow transducers, said calibrator measuring pressure transducer signals at two known pressure levels and flow transducer signals at two known flows and transmitting the measurements to said processor, said calibrator including a water-filled outer column, a vertically aligned inner tube, and tubing connecting the inner tube to the inspiration port.

12. The ventilator system of claim 11 , wherein said processor assumes a straight line relationship between pressure levels and pressure signals, and between flow levels and flow signals.

13. The ventilator system of claim 11 , wherein the first flow signal is zero, and the second flow signal is determined based on the volume of the inner tube and the time required to empty water from the inner tube.

14. The ventilator system of claim 11 , wherein the first pressure signal is zero and the second pressure signal is determined by the pressure required to fill the inner tube with water.

15. The ventilator system of claim 11 , including pressure transducers to measure lung pressure, mouth pressure and reservoir pressure, said processor calibrating each of said transducers based an information received from said calibrator.

16. A method of calibrating transducers within a respiratory ventilation system including a ventilator having an air conduit, inspiration and expiration ports, pressure and flow transducers adapted to emit signals proportional to the levels of air pressure and air flow within said conduit, said ventilator being controlled by a processor comprising:

a) providing a calibrator including a water-filled outer column, a vertically aligned inner tube, tubing connecting the inner tube to the inspiration port;

b) measuring pressure transducer signals at two known pressure levels and flow transducer signals at two known flows and transmitting the measurements to said processor; and

c) calibrating said pressure and flow transducer with said processor from said pressure and flow signals assuming that there is a straight line relationship between the two pressure signals and the two flow signals.

17. The method of claim 16 , wherein one of said pressure levels is measured when the water levels in the outer column and the inner tube are the same and the second signal is measured when the inner tube is filled with pressurized air.

18. The method of claim 16 , wherein the first flow signal is measured when there is no flow, and the second signal is determined by measuring the flow of air from the inner tube after the inner tube has been filled with air.

19. The method of claim 16 , wherein said transducers are calibrated assuming a straight line relationship between pressure levels and pressure signals, and between flow levels and flow signals.

20. The method of claim 16 , wherein said ventilator system includes pressure transducers to measure lung pressure, mouth pressure and reservoir pressure, said method including calibrating each of said transducers based on information received from said calibrator.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded Dec 18, 2025
From: CITIZENS BANK, N.A.
To: HARVARD BIOSCIENCE, INC.; DATA SCIENCES INTERNATIONAL, INC.
Reel/Frame 074022/0661 →
RELEASE OF SECURITY INTEREST IN PATENTS Recorded Dec 29, 2020
From: CERBERUS BUSINESS FINANCE, LLC
To: HOEFER, INC.; HARVARD BIOSCIENCE, INC.; WARNER INSTRUMENTS LLC; BIOCHROM LIMITED; TRIANGLE BIOSYSTEMS, INC.; DATA SCIENCES INTERNATIONAL, INC.
Reel/Frame 054866/0502 →
SECURITY INTEREST Recorded Dec 28, 2020
From: HARVARD BIOSCIENCE, INC.
To: CITIZENS BANK, N.A.
Reel/Frame 054855/0481 →
ASSIGNMENT FOR SECURITY -- PATENTS Recorded Feb 1, 2018
From: HOEFER, INC.; HARVARD BIOSCIENCE, INC.; WARNER INSTRUMENTS LLC; BIOCHROM LIMITED; TRIANGLE BIOSYSTEMS, INC.; DATA SCIENCES INTERNATIONAL, INC.
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 045219/0441 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2014
From: BUXCO ELECTRONICS, INC.
To: DATA SCIENCES INTERNATIONAL, INC.
Reel/Frame 031927/0480 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2008
From: LOMASK, JOSEPH; LARSON, RICHARD ALVIN
To: BUXCO ELECTRONICS, INC.
Reel/Frame 020803/0306 →