IP Library › Granted Patent US 8,313,760
Granted Patent B2
US 8,313,760 · App. 12/107,629 · Granted Nov 20, 2012

Compositions and methods for coating medical implants

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Quick Facts
Patent No.
US 8,313,760
App. No.
12/107,629
Granted
Nov 20, 2012
Kind
B2
Abstract

Medical implants are provided which release a fluoropyrimidine or an analog thereof, thereby inhibiting or reducing the incidence of infection associated with the implant.

Claims (8)

1. A method for reducing or inhibiting infection associated with a medical implant, comprising the step of introducing into a patient a medical implant which has been covered or coated with an antimicrobially effective amount of a fluoropyrimidine or an analog thereof.

2. The method according to claim 1 wherein said fluoropyrimidine is 5-fluorouracil.

3. The method according to claim 1 wherein said fluoropyrimidine is floxuridine.

4. The method according to claim 1 wherein said composition further comprises a polymer.

5. The method according to claim 4 wherein said polymer is a non-biodegradable polymer.

6. The method according to claim 4 wherein said polymer is a polyurethane, cellulose or a cellulose-derived polymer, or a combination of polyurethane and cellulose or a cellulose-derived polymer.

7. The method according to claim 1 wherein said medical implant is a vascular catheter.

8. The method according to claim 1 wherein said medical implant is a dialysis catheter.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 13, 2008
From: HUNTER, WILLIAM L.; GRAVETT, DAVID M.; TOLEIKIS, PHILIP M.; LIGGINS, RICHARD T.; LOSS, TROY A.E.
To: ANGIOTECH INTERNATIONAL AG
Reel/Frame 021829/0554 →