Baroreflex activation for pain control, sedation and sleep
Systems and methods provide baroreflex activation to treat or reduce pain and/or to cause or enhance sedation or sleep. Methods involve activating the baroreflex system to provide pain reduction, sedation, improved sleep or some combination thereof. Systems include at least one baroreflex activation device, at least one sensor for sensing physiological activity of the patient, and a processor coupled with the baroreflex activation device(s) and the sensor(s) for processing sensed data received from the sensor and for activating the baroreflex activation device. In some embodiments, the system is fully implantable within a patient, such as in an intravascular, extravascular or intramural location.
1. A system for effecting a change in a baroreflex system of a patient to treat or reduce pain, the system comprising:
a baroreflex activation device including an electrode configured to be implanted on or in a blood vessel proximate a baroreceptor within a wall of the vessel;
a sensor for sensing a patient condition indicative of pain; and
an implantable processor coupled with the baroreflex activation device and the sensor for processing sensed data received from the sensor indicative of pain, and in response for activating the baroreflex activation device so as to stimulate the baroreceptor via the electrode.
2. A system as in claim 1 , wherein the system is fully implantable within the patient.
3. A system as in claim 2 , wherein the baroreflex activation device is implantable such that the electrode is in a lumen of the blood vessel.
4. A system as in claim 1 , wherein the baroreflex activation device is adapted to provide at least one of continuous activation, pulsed activation and periodic activation.
5. The system of claim 1 , wherein the sensor is adapted to sense physiological activity of the patient indicative of pain.
6. The system of claim 1 , wherein the sensor is adapted to sense neurological activity of the patient indicative of pain.
7. A system as in claim 2 , wherein the baroreflex activation device is implantable such that the electrode is extravascular.
8. A system as in claim 7 , wherein the baroreflex activation device is implantable such that the electrode is on an outside surface of the blood vessel.