Granted Patent
B2
US 7,919,625 · App. 12/139,834 · Granted Apr 5, 2011
4-anilino-3-quinolinecarbonitriles for the treatment of chronic myelogenous leukemia (CML)
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Abstract
Compounds of the formula: wherein: n is an integer from 1-3; X is N, CH, provided that when X is N, n is 2 or 3; R is alkyl of 1 to 3 carbon atoms; R 1 is 2,4-diCl, 5-OMe; 2,4-diCl; 3,4,5-tri-OMe; 2-Cl, 5-OMe; 2-Me, 5-OMe; 2,4-di-Me; 2,4-diMe-5-OMe, 2,4-diCl, 5-OEt; R 2 is alkyl of 1 to 2 carbon atoms, and pharmaceutically acceptable salts thereof.
Claims (1)
1. A pharmaceutical composition comprising a CML inhibiting amount of the compound 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile.
Assignments (3)
ASSIGNEE ADDRESS CORRECTION
Recorded Mar 27, 2023
From: WYETH LLC
To: WYETH LLC
Reel/Frame 063165/0455 →
CHANGE OF ADDRESS FOR ASSIGNEE
Recorded Aug 16, 2016
From: WYETH LLC
To: WYETH LLC
Reel/Frame 039743/0965 →