Endoluminal device including a mechanism for proximal or distal fixation, and sealing and methods of use thereof

1. An endoluminal device, comprising:

a stent;

a tubular graft supported by the stent, wherein the graft comprises at least a proximal opening and a distal opening; and

a variable diameter ring at or adjacent at least one of said openings, wherein the variable diameter ring comprises a coiled length of wire having two ends and forming substantially at least one winding around the tubular graft, wherein the coiled length of wire has a head end and a tail end, the head end having a loop through which the tail end of the wire passes.

2. The endoluminal device of claim 1 , wherein the ring is a nitinol ring.

3. The endoluminal device of claim 1 , wherein the ring is a self-expanding ring or a balloon-expandable ring.

4. The endoluminal device of claim 1 , wherein the ring has a plurality of windings.

5. The endoluminal device of claim 4 , wherein the ring has at least five windings.

6. The endoluminal device of claim 1 , wherein the wire has a diameter in the range from about 0.005 cm to about 0.008 cm (about 0.002 inches to about 0.003 inches).

7. The endoluminal device of claim 1 , further comprising at least one additional variable diameter ring at or adjacent both of said openings.

8. The endoluminal device of claim 1 , wherein the stent is a self-expanding stent or a balloon-expandable stent.

9. The endoluminal device of claim 1 , wherein the stent is a nitinol stent.

10. The endoluminal device of claim 1 , comprising a plurality of stents.

11. The endoluminal device of claim 1 , wherein the tubular graft comprises an extracellular matrix material.

12. The endoluminal device of claim 11 , wherein the extracellular matrix material is a small intestine submucosa material.

13. The endoluminal device of claim 1 , further comprising a lubricant, wherein the lubricant is applied to the coiled length of wire.

14. The endoluminal device of claim 1 , further comprising a hydrophilic coating.

15. The endoluminal device of claim 1 , wherein the variable diameter ring is covered by a cuff in the tubular graft.

16. The endoluminal device of claim 15 , wherein the cuff is an external cuff or an internal cuff.

17. An endoluminal device comprising:

a stent;

a branched tubular graft supported by the stent, wherein the graft comprises at least a proximal opening and two distal openings; and

a variable diameter ring at or adjacent at least one of said openings, wherein the variable diameter ring comprises a coiled length of wire having two ends and forming substantially at least one winding around the tubular graft, wherein the coiled length of wire has a head end and a tail end, the head end having a loop through which the tail end of the wire passes.

18. An endoluminal device, comprising:

a stent;

a tubular graft supported by the stent, wherein the graft comprises at least a proximal opening and a distal opening, the endoluminal device having a compressed state and an expanded state; and

a variable diameter ring at or adjacent at least one of said openings, wherein the variable diameter ring comprises a coiled length of wire having two ends and forming substantially at least one winding around the tubular graft in the expanded state, wherein the coiled length of wire has a head end and a tail end, the head end having a loop through which the tail end of the wire passes,

wherein an initial number of windings of the variable diameter ring in the compressed state is a product of an expansion ratio and a number of windings in the expanded state;

wherein the expansion ratio is a ratio of an expanded stent graft diameter by a compressed stent graft diameter; and

wherein a length of wire is equal to a result of multiplying the number of initial wire windings by Pi (π) and by the expanded stent graft diameter.