Ocular implant with hydrogel expansion capabilities
View Patent ↗An ocular implant includes an elongate member having an internal lumen forming a flow pathway that provides a fluid pathway between the anterior chamber and the suprachoroidal space of the eye. The implant includes a hydrogel member attached to the elongate member, wherein the hydrogel member is adapted to expand upon implantation of the elongate member in the eye. An attachment attaches the hydrogel member to the elongate member.
1. An ocular implant, comprising:
an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway, wherein the elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber and at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber toward the suprachoroidal space when the elongate member is implanted in the eye;
an anchor member attached to the elongate member, wherein the anchor member is at least partially formed of a hydrogel, and wherein the anchor member is adapted to expand radially outward relative to a longitudinal axis of the elongate member upon implantation of the elongate member in the eye such that the anchor member expands outward to a radial dimension that forms a maximum radial dimension of the ocular implant;
a mechanical attachment attached to the elongate member that holds the anchor member adjacent to the elongate member, wherein the anchor member is positioned inside the mechanical attachment.
2. An ocular implant as in claim 1 , wherein the mechanical attachment further comprises a layer of acrylic, the acrylic being attached to the anchor member.
3. An ocular implant as in claim 2 , wherein the acrylic is covalently bonded to the anchor member.
4. An ocular implant as in claim 2 , wherein the anchor member is covalently bonded to acrylic pursuant to a polymerization process.
5. An ocular implant as in claim 1 , wherein the mechanical attachment comprises a cage.
6. An ocular implant as in claim 5 , wherein the anchor member expands through slots in the cage.
7. An ocular implant as in claim 1 , wherein the mechanical attachment further comprises a semi-permeable membrane coated over the anchor member and the elongate member.
8. An ocular implant as in claim 7 , wherein the membrane expands with the anchor member.
9. An ocular implant as in claim 7 , wherein the membrane is water-permeable to permit hydration of the anchor member through the membrane.
10. An ocular implant as in claim 1 , further comprising a resorbable coating positioned over the anchor member.
11. An ocular implant as in claim 10 , wherein the resorbable coating regulates a rate of expansion of the anchor member.
12. An ocular implant as in claim 10 , wherein the coating bursts upon expansion of the anchor member.
13. An ocular implant as in claim 1 , wherein the mechanical attachment comprises a pair of plates positioned on the elongate member and wherein the anchor member is positioned between the plates.
14. An ocular implant as in claim 1 , wherein the anchor member causes a portion of the implant to move upon expansion of the anchor member.