LARGE DOSE RIBAVRIN FORMULATONS
The present invention is related to pharmaceutical dosage forms of ribavirin which are designed to increase patient compliance to a ribavirin therapy. Examples of such dosage forms include 400 mg to 600 mg tablets. These dosage forms are bioequivalent to multiple doses of tablets containing small amounts of ribavirin.
1 . A daily dosage regimen of ribavirin treatment comprising administering to a patient in need thereof exactly one dosage form of ribavirin and 8 hours to 16 hours later administering another one dosage form of ribavirin.
2 . The daily dosage regimen of claim 1 , wherein the dosage form comprises 400 mg to 600 mg of ribavirin.
3 . The daily dosage regimen of claim 2 , wherein the dosage form is a tablet which comprises 400 mg of ribavirin.
4 . The daily dosage regimen of claim 3 , wherein the dosage form is a tablet which comprises 600 mg of ribavirin.