IP Library › Granted Patent US 8,124,632
Granted Patent B2
US 8,124,632 · App. 12/184,760 · Granted Feb 28, 2012

Alkylsulfonyl-substituted thiazolide compounds

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Quick Facts
Patent No.
US 8,124,632
App. No.
12/184,760
Granted
Feb 28, 2012
Kind
B2
Abstract

A new class of alkylsulfonyl-substituted thiazolide compounds is described. These compounds show strong activity against hepatitis virus.

Claims (2)

1. A method for treating Hepatitis C Virus infection comprising administering an effective amount of pharmaceutical composition comprising a compound of formula (I)

wherein one of R 6 or R 9 is C1-C6 alkylsufonyl, and the other is hydrogen; wherein R1 is a hydroxyl group; and wherein R 2 to R 5 are hydrogen, or a pharmaceutically acceptable salt or ester thereof and a carrier to a patient in need thereof.

Assignments (11)
SECURITY INTEREST Recorded Nov 16, 2019
From: ROMARK BIOSCIENCES S.À R.L. LLC; ROMARK LABORATORIES, L.C.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 051030/0613 →
SECURITY INTEREST Recorded Jul 2, 2018
From: ROMARK BIOSCIENCES S.À R.L. LLC; ROMARK LABORATORIES, L.C.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 046254/0524 →
SECURITY INTEREST Recorded Dec 22, 2017
From: ROMARK BIOSCIENCES S.À R.L. LLC; ROMARK LABORATORIES, L.C.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 044472/0001 →
RELEASE OF SECURITY INTEREST Recorded Mar 6, 2015
From: U.S. BANK NATIONAL ASSOCIATION
To: ROMARK LABORATORIES, L.C.; ROMARK MANUFACTURING, LLC; LAPICOR, N.V.
Reel/Frame 035108/0474 →
SECURITY AGREEMENT Recorded Sep 4, 2013
From: ROMARK LABORATORIES, L.C.; ROMARK MANUFACTURING, LLC; LAPICOR, N.V.
To: U.S. BANK NATIONAL ASSOCIATION
Reel/Frame 031156/0923 →
RELEASE OF SECURITY INTEREST Recorded Sep 3, 2013
From: PAUL CAPITAL FUND MANAGEMENT, L.L.C.
To: ROMARK LABORATORIES, L.C.
Reel/Frame 031159/0636 →
CHANGE OF NAME Recorded Jul 29, 2011
From: LAMINAR DIRECT CAPITAL L.P.
To: LAMINAR DIRECT CAPITAL, L.L.C. (FORMERLY KNOWN AS LAMINAR DIRECT CAPITAL L.P.)
Reel/Frame 026676/0386 →
RELEASE OF SECURITY INTEREST Recorded Jul 29, 2011
From: LAMINAR DIRECT CAPITAL, L.L.C. (FORMERLY KNOWN AS LAMINAR DIRECT CAPITAL L.P.)
To: ROMARK LABORATORIES, L.C.
Reel/Frame 026676/0576 →
SECURITY AGREEMENT Recorded Jul 29, 2011
From: ROMARK LABORATORIES, L.C.
To: PAUL CAPITAL FUND MANAGEMENT, L.L.C.
Reel/Frame 026676/0635 →
NOTICE OF GRANT OF SECURITY INTEREST IN PATENTS Recorded Sep 28, 2009
From: ROMARK LABORATORIES, L.C.
To: LAMINAR DIRECT CAPITAL, L.L.C., AS COLLATERAL AGENT
Reel/Frame 023282/0880 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2008
From: ROSSIGNOL, JEAN-FRANCOIS; SEMPLE, J. EDWARD
To: ROMARK LABORATORIES L.C.
Reel/Frame 021530/0305 →