Trained and adaptive response in a neurostimulator

1. An implantable neurostimulator, comprising:

a pulse generator configured to provide a first neurostimulation therapy to a neural structure in a patient;

control logic coupled to the pulse generator;

a plurality of physiological parameter sensors coupled to the control logic, wherein the control logic is configured to:

sense at least two physiological parameters in a body of the patient, the at least two physiological parameters including at least two of an action potential in a cranial nerve, a heart parameter, a temperature, and a blood parameter;

for each of the at least two physiological parameters, generate a first series of signals representative of the physiological parameters sensed over a first time period, store each of the first series of signals as a time sequence data stream representative of the physiological parameters, and transmit each time sequence data stream to an analyzer external to the patient; and

wherein the control logic is further configured to receive marker information from the analyzer indicative of an occurrence of a physiological event based on the first series of signals representative of the physiological parameters sensed over a first time period and again sense the at least two physiological parameters in the body of the patient, for each of the at least two physiological parameters, the control logic is further configured to generate a second series of signals representative of the physiological parameters sensed, and analyze each of the second series of signals to determine whether at least one marker from the marker information is present.

2. The implantable neurostimulator of claim 1 wherein the control logic is further configured to cause a second stimulation therapy to be provided to a cranial nerve in the patient when the at least one marker is present in the second series of signals.

3. The implantable neurostimulator of claim 2 wherein the first and second stimulation therapies are characterized by a plurality of parameters, and the parameters for first and second stimulation therapies are programmed the same.

4. The implantable neurostimulator of claim 1 wherein the control logic is configured to receive the marker information at or near the beginning of the physiological event.

5. The implantable neurostimulator of claim 1 wherein the control logic is configured to receive the marker information after the physiological event.

6. The implantable neurostimulator of claim 1 wherein the control logic is configured to store a timestamp with each stored time sequence data stream.

7. The implantable neurostimulator of claim 1 , further comprising a device selected from a transceiver, a Reed switch, and an accelerometer, and wherein the control logic is configured to receive the marker information from the device.

8. An implantable neurostimulator, comprising:

a pulse generator configured to provide a first neurostimulation therapy to a vagus nerve in a patient;

control logic coupled to the pulse generator;

a plurality of physiological parameter sensors coupled to the control logic, wherein the control logic is configured to:

sense a temperature and a heart rate in body of the patient;

for each of the temperature and the heart rate, generate a first series of signals representative of the temperature and the heart rate sensed over a first time period, store each of the first series of signals as a time sequence data stream representative of the temperature and the heart rate, and transmit each time sequence data stream to an analyzer external to the patient; and

wherein the control logic is further configured to receive marker information from the analyzer indicative of an occurrence of a physiological event based on the first series of signals representative of the temperature and the heart rate and again sense the temperature and the heart rate in the body of the patient, for each of the temperature and the heart rate, the control logic is configured to generate a second series of signals representative of the temperature and the heart rate sensed over a second time period, and analyze each of the second series of signals to determine whether at least one marker from the marker information is present.

9. The implantable neurostimulator of claim 8 wherein the control logic is further configured to cause a second stimulation therapy to be provided to the vagus nerve in the patient when the marker is present in the second series of signals.

10. The implantable neurostimulator of claim 8 wherein the first and second neurostimulation therapies are characterized by a plurality of parameters, and the parameters for first and second stimulation therapies are programmed the same.

11. The implantable neurostimulator of claim 8 wherein the control logic is configured to receive the marker information at or near the beginning of the physiological event.

12. The implantable neurostimulator of claim 8 wherein the control logic is configured to receive the marker information after the physiological event.

13. The implantable neurostimulator of claim 8 wherein the control logic is further configured to store a timestamp with each stored time sequence data stream.

14. The implantable neurostimulator of claim 8 , further comprising a device selected from a transceiver, a Reed switch, and an accelerometer, and wherein the control logic is configured to receive the marker information from the device.