IP Library Granted Patent US 8,881,894
Granted Patent B2
US 8,881,894 · App. 12/195,788 · Granted Nov 11, 2014

Multiple-compartment applicator

Inventors: John C. Castel (Reno, NV); R. Patrick Abergel (Santa Monica, CA)
Assignee: Sonovia Holdings LLC
A61K9/7023A61K31/375
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Quick Facts
Patent No.
US 8,881,894
App. No.
12/195,788
Granted
Nov 11, 2014
Kind
B2
Abstract

A multiple-compartment ascorbic acid delivery unit is provided. The first compartment is impermeable to oxygen and ultraviolet light and contains a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters. The second compartment is liquid impermeable and contains a pharmaceutically acceptable carrier system. The first compartment is entirely enclosed within said second compartment or vice versa. An opening is formed in the inner compartment in order to combine the contents of the two compartments to form an ascorbic acid carrier composition prior to delivery to the patient.

Claims (48)

1. A multiple-compartment ascorbic acid delivery unit comprising:

an outer compartment containing a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters, wherein said outer compartment is impermeable to oxygen and ultraviolet light;

an inner compartment containing a pharmaceutically acceptable carrier system, wherein said inner compartment is liquid impermeable, wherein said inner compartment is entirely enclosed within said outer compartment; and

an absorbent structure selected from the group consisting of a wipe, a patch, a pad, and a mask, said absorbent structure located within said outer compartment or said inner compartment, and wherein said absorbent structure is adapted to absorb and transfer an ascorbic acid carrier composition comprising a mixture of said solid vitamin-containing composition and said pharmaceutically acceptable carrier system to an intended surface;

wherein said inner compartment includes a breakable barrier integrally formed therein such that when said breakable barrier is broken said vitamin-containing composition and said pharmaceutically acceptable carrier system are capable of being combined to form said ascorbic acid carrier composition;

wherein said outer compartment includes a marking corresponding to said breakable barrier for applying pressure to said outer compartment at a predetermined location in order to break said breakable barrier.

2. The delivery unit of claim 1 , wherein said breakable barrier comprises a declivity, score line, or frangible seal in said inner compartment.

3. The delivery unit of claim 1 , wherein said outer compartment is comprised of a material selected from the group consisting of a deformable metal or polymer, aluminized or metalized polymer, polycarbonate, polyethylene, vinyl, and polyethylene terephthalate polyester film.

4. The delivery unit of claim 1 , wherein said outer compartment further comprises a gated opening having an open position and a closed position, wherein when said gated opening is in said open position said ascorbic acid carrier composition can pass through said gated opening and when said gated opening is in said closed position said ascorbic acid carrier composition remains confined within said outer compartment.

5. The delivery unit of claim 1 , wherein said absorbent structure is selected from the group consisting of a woven material, a nonwoven material, an open-cell foam, a semi-open-cell foam, felt, and hydrogel, collagen, and hydrocolloid laminates.

6. The delivery unit of claim 5 , wherein said absorbent structure is enclosed within said outer compartment, and wherein said absorbent structure is coupled to said outer compartment.

7. The delivery unit of claim 5 , wherein said absorbent structure is enclosed within said outer compartment, and wherein said absorbent structure is impregnated with said solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters.

8. The delivery unit of claim 5 , wherein said absorbent structure is enclosed within said inner compartment, and wherein said absorbent structure is coupled to said inner compartment.

9. The delivery unit of claim 5 , wherein said absorbent structure has an abrasive material on at least a portion of its surface or said abrasive material is impregnated within said absorbent structure.

10. The delivery unit of claim 1 , wherein said outer compartment further includes a means for exposing said ascorbic acid carrier composition to the environment.

11. The delivery unit of claim 10 , wherein said means for exposing said ascorbic acid carrier composition comprises at least one tear notch, whereby said at least one tear notch allows a user to tear away a portion of said outer compartment.

12. The delivery unit of claim 10 , wherein said means for exposing said ascorbic acid carrier composition comprises a frangible seal formed in said outer compartment.

13. The delivery unit of claim 1 , wherein said pharmaceutically acceptable carrier system comprises water.

14. The delivery unit of claim 13 , wherein said pharmaceutically acceptable carrier system further comprises one or more organic solvents miscible with water.

15. The delivery unit of claim 13 , wherein said pharmaceutically acceptable carrier system further comprises one or more therapeutic agents, chelators, or pH regulators.

16. The delivery unit of claim 1 , wherein said pharmaceutically acceptable carrier system comprises one or more therapeutic agents selected from the group consisting of antioxidants, growth factors, hormones, growth inhibitors, vitamins, exfoliators, skin toners, lubricants, hydrators, muscle relaxers, muscle toners, and skin protectors.

17. The delivery unit of claim 1 , wherein said solid vitamin-containing composition comprises at least two solid antioxidants.

18. A multiple-compartment ascorbic acid delivery unit comprising:

an outer compartment containing a pharmaceutically acceptable carrier system, wherein said outer compartment is liquid impermeable, wherein said outer compartment is impermeable to oxygen and ultraviolet light;

an inner compartment containing a solid vitamin-containing composition comprising ascorbic acid or its pharmaceutically acceptable salts and esters, wherein said inner compartment is entirely enclosed within said outer compartment;

an absorbent structure comprising a hydrogel or hydrocolloid laminate selected from the group consisting of a wipe, a patch, a pad, and a mask, said absorbent structure located within said inner compartment or said outer compartment, and wherein said absorbent structure is adapted to absorb and transfer an ascorbic acid carrier composition comprising a mixture of said solid vitamin-containing composition and said pharmaceutically acceptable carrier system to an intended surface;

wherein said inner compartment includes a means for combining said solid vitamin-containing composition and said pharmaceutically acceptable carrier system to form said ascorbic acid carrier composition, and wherein said means for combining comprises a breakable barrier integrally formed in said inner compartment such that when said breakable barrier is broken said vitamin-containing composition and said pharmaceutically acceptable carrier system are capable of being combined to form said ascorbic acid carrier composition; and

wherein said outer compartment includes a marking thereon for applying pressure to said outer compartment at a predetermined location in order to break said breakable barrier.

19. The delivery unit of claim 18 , wherein said breakable barrier comprises a declivity, score line, or frangible seal in said inner compartment.

20. The delivery unit of claim 18 , wherein said inner compartment is comprised of a material selected from the group consisting of a deformable metal or polymer, aluminized or metalized polymer, polycarbonate, polyethylene, vinyl, and polyethylene terephthalate polyester film.

21. The delivery unit of claim 18 , wherein said outer compartment further comprises a gated opening having an open position and a closed position, wherein when said gated opening is in said open position said ascorbic acid carrier composition can pass through said gated opening and when said gated opening is in said closed position said ascorbic acid carrier composition remains confined within said outer compartment.

22. The delivery unit of claim 18 , wherein said absorbent structure is coupled to said outer compartment.

23. The delivery unit of claim 18 , wherein said absorbent structure has an abrasive material on at least a portion of its surface or said abrasive material is impregnated within said absorbent structure.

24. The delivery unit of claim 18 , wherein said outer compartment includes a means for exposing said ascorbic acid carrier composition to the environment.

25. The delivery unit of claim 24 , wherein said means for exposing said ascorbic acid carrier composition comprises at least one tear notch, whereby said at least one tear notch allows a user to tear away a portion of said outer compartment.

26. The delivery unit of claim 24 , wherein said means for exposing said ascorbic acid carrier composition comprises a frangible seal formed in said outer compartment.

27. The delivery unit of claim 18 , wherein said pharmaceutically acceptable carrier system comprises water.

28. The delivery unit of claim 27 , wherein said pharmaceutically acceptable carrier system further comprises one or more organic solvents miscible with water.

29. The delivery unit of claim 27 , wherein said pharmaceutically acceptable carrier system further comprises one or more therapeutic agents, chelators, or pH regulators.

30. The delivery unit of claim 27 , wherein said pharmaceutically acceptable carrier system comprises one or more therapeutic agents selected from the group consisting of antioxidants, growth factors, hormones, growth inhibitors, vitamins, exfoliators, skin toners, lubricants, hydrators, muscle relaxers, muscle toners, and skin protectors.

31. The delivery unit of claim 18 , wherein said solid vitamin-containing composition comprises at least two solid antioxidants.

32. A multiple compartment ascorbic acid delivery kit, said kit comprising the combination of:

a multiple-compartment ascorbic acid delivery unit according to claim 1 ; and

a set of instructions for breaking said breakable barrier, mixing said solid vitamin-containing composition and said pharmaceutically acceptable carrier system together to form said ascorbic acid carrier composition, and transferring said ascorbic acid carrier composition to said intended surface.

33. The multiple compartment ascorbic acid delivery kit of claim 32 wherein said set of instructions further comprise absorbing said ascorbic acid carrier composition with said absorbent material in order to transfer said ascorbic acid carrier composition to said intended surface.

34. The multiple compartment ascorbic acid delivery kit of claim 32 further comprising an abrasive material, and wherein said set of instructions further comprise abrading said intended surface with said abrasive material prior to or simultaneous with said transferring.

35. The multiple compartment ascorbic acid delivery kit of claim 32 , wherein said pharmaceutically acceptable carrier system comprises one or more therapeutic agents selected from the group consisting of antioxidants, growth factors, hormones, growth inhibitors, vitamins, exfoliators, skin toners, lubricants, hydrators, muscle relaxers, muscle toners, and skin protectors in said carrier system.

36. The multiple compartment ascorbic acid delivery kit of claim 32 , wherein said solid vitamin-containing composition further comprises at least two solid antioxidants.

Assignments (6)
RELEASE OF SECURITY INTEREST Recorded May 14, 2020
From: MAISON CASTEL, LLC
To: CAREWEAR CORP.
Reel/Frame 052658/0360 →
SECURITY INTEREST Recorded Feb 16, 2018
From: CAREWEAR CORP.
To: MAISON CASTEL, LLC
Reel/Frame 044952/0694 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 7, 2018
From: SONOVIA HOLDINGS LLC
To: CAREWEAR CORP.
Reel/Frame 044854/0812 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 3, 2014
From: LABORATOIRE NATUREL PARIS, LLC
To: MAISON CASTEL, LLC
Reel/Frame 031886/0189 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 3, 2014
From: MAISON CASTEL, LLC
To: SONOVIA HOLDINGS LLC
Reel/Frame 031886/0603 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 21, 2008
From: CASTEL, JOHN C.; ABERGEL, R. PATRICK
To: LABORATOIRE NATUREL PARIS, LLC
Reel/Frame 021424/0261 →
Continuity (1)
Related Publication 20100047326A1 · Feb 25, 2010