Regional oxygen uptake/perfusion measuring device and method
View Patent ↗To assess regional oxygen uptake and/or perfusion in a patient, a volume of air inhaled by the patient is determined and, according to a method of electrical impedance tomography, a first regional lung volume is measured at a first time point of a breathold procedure. The first regional lung volume is compared to a second regional lung volume at a second time point of the breathold procedure.
1. A device comprising:
an electrical impedance tomography (EIT) device configured to measure a regional lung volume without use of a contrast marker,
wherein the device is configured to:
measure with the EIT a first regional lung volume at a first time point of a breathold procedure and at a second time point of the breathold procedure;
determine a change in the first regional lung volume; and
determine a first regional oxygen uptake based at least in part on the change in the first regional lung volume.
2. The device of claim 1 , wherein the device is further configured to perform a volume calibration at a time outside of the breathold procedure.
3. The device of claim 1 , wherein the device is further configured to measure with the EIT a second regional lung volume at the first and second time points of the breathold procedure and determine a change in the second regional lung volume.
4. The device of claim 3 , wherein the device is further configured to determine a first regional oxygen uptake and a second regional oxygen uptake based at least in part on the respective changes in first and second regional lung volumes.
5. The device of claim 1 , wherein the device is further configured to measure the first regional lung volume at the first and second time points of a breathold procedure performed at any breath point between a full exhalation and a full inhalation.
6. A method of determining regional oxygen uptake, the method comprising the steps of:
measuring with an electrical impedance tomography (EIT) device, and without use of a contrast marker, a first regional lung volume at a first time point of a breathold procedure;
measuring with the EIT device, and without use of a contrast marker, the first regional lung volume at a second time point of the breathold procedure;
determining a change in the first regional lung volume; and
determining a first regional oxygen uptake based at least in part on the change in first regional lung volume.